Abstract Details

Title Factors Associated to Intrahospital Mortality in Neurological Infections in a Tertiary Center in Bogota

Topic General Neurology

Presentation(s) P3 - Poster Session 3 (5:30 PM-6:30 PM)

Poster/Presentation
Number 15-001

Objective

To establish risk factors associated with mortality and poor outcomes in patients with neuroinfectious disorders a tertiary center in Bogota, Colombia.

Background Neuroinfectious disorders continue to be a leading cause of morbidity and mortality in the young population. In underserved areas, higher levels of advanced immunosuppression due to HIV worsen the prognosis of these patients and impose higher rates of intrahospital mortality.

Design/Methods

Descriptive, cross-sectional study, evaluated patients with neuroinfectious disorders from 2019- 2022. The modified Rankin scale (mRs) was calculated for each patient at the time of the last evaluation. Parametric and non-parametric tests were used to analyze risk factors associated to poor outcomes (mRs > 3) and death (mRs=6) by the time of discharge.

Results We identified a total of 200 patients with a median age of 37 (IQR 28-55). Most of the patients were male (n=152, 76%) and the migrant population constituted approximately 20% of our cohort (n=41, 20.5%). Immunosuppression due to Human Immunodeficiency Virus (HIV) was documented in 125 (62.5%) patients. The percentage of intrahospital mortality was 26.5% (n=41) with a median of 38 years (IQR 31-77). Factors associated with mortality were lower CD4 counts (0.053), especially if lower than 200 (p=0.039), and the absence of antiretroviral therapy (p=0.084).

Conclusions

Neuroinfectious disorders continue to impose high mortality rates in the young population, especially in underserved areas where advanced HIV is prevalent.

Authors/Disclosures
Juan D. Martinez Lemus, MD (The University of Texas Health Science Center at Houston) PRESENTER	Dr. Martinez Lemus has nothing to disclose.
Angela Villamil Saldarriaga (Hospital Simón Bolivar)	Miss Villamil Saldarriaga has nothing to disclose.
Alejandra Moncaleano Calderón (Hospital Simón Bolívar)	No disclosure on file
Karen Mesa Santamaria	No disclosure on file
Maria I. Reyes, MD (Hospital Simon Bolivar)	Dr. Reyes has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Merck. Dr. Reyes has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Biogen. Dr. Reyes has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Novartis. Dr. Reyes has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Roche. Dr. Reyes has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Novartis. Dr. Reyes has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Novartis.

��ɫ��

��ɫ��