Abstract Details

Title MRI Analysis of Relationships Between Different Visual Centers in the Brain: A Voxel-based Morphology Analysis

Topic Neuro-ophthalmology/Neuro-otology

Presentation(s) P7 - Poster Session 7 (11:45 AM-12:45 PM)

Poster/Presentation
Number 10-003

Objective The main goal of our research is to conduct a thorough comparative investigation of the structural elements of the visual pathway.

Background Different brain areas play a significant role in the visual process, although many areas are still under study. The exploration and study of the human brain's visual pathway relies heavily on magnetic resonance imaging (MRI).

Design/Methods We analyzed the results of 27 MRI scans of a healthy patient dataset. Analysis was done using Statistical Parametric Mapping (SPM) Version 12, a statistical software embedded in MATLAB. For segmentation purposes, we used a toolbox within SPM 12, CAT12 (Computational Anatomy Toolbox).

Results The strongest positive correlations were between the right and left Cuneus grey matter (r2 = 0.96, p < 0.01). There was a strong positive correlation between the left Middle Occipital Gyrus grey matter and Left area hOc4la of Lower Occipital Cortex grey matter (r2 = 0.87, p < 0.01), and between the Right area hOc4la of Lower Occipital Cortex grey matter and Right Middle Occipital Gyrus grey matter (r2 = 0.8, p < 0.01). Left area hOc2 of V2 grey matter had strong positive correlations with many areas including the bilateral area hOc3d of Cuneus (with the bilateral area hOc3 of V2 grey matter), the bilateral Lingual gyrus grey matter, the right area hOc2 of V2 grey matter, the left area hOc3v of Lingual gyrus grey matter and left Inferior Occipital Gyrus grey matter, as well as both the grey and white matter of left area hOc1 of V1. The right area hOc2 of V2 grey matter had similar connections to the contralateral corresponding structures.

Conclusions Many strong positive correlations exist between possible and established vision centers in the brain, hinting at their major involvement in the vision pathway.

Authors/Disclosures
Hamza K. Alsalhi PRESENTER	Dr. Alsalhi has nothing to disclose.
Amr Hassan, MD	Dr. Hassan has nothing to disclose.
Mohamed Zeyada	Dr. Zeyada has nothing to disclose.
Taha Nagib	No disclosure on file
Sadeen Eid	Sadeen Eid has nothing to disclose.
Ahmad Abusharkh	No disclosure on file
Hany Atwan	Mr. Atwan has nothing to disclose.
Benyameen Mosa	No disclosure on file
Hashem Abu Serhan (Hamad Medical Corporation)	Hashem Abu Serhan has nothing to disclose.
Ahmed Negida, MD, PhD (Virginia Commonwealth University)	Dr. Negida has nothing to disclose.

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