Abstract Details

Title Evaluation of Transcranial Magnetic Stimulation and Transcranial Direct Current Stimulation in the Gait of Patients with Multiple Sclerosis: A Systematic Review

Topic Neuro-rehabilitation

Presentation(s) P7 - Poster Session 7 (11:45 AM-12:45 PM)

Poster/Presentation
Number 11-009

Objective This study aimed to evaluate the effects of transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS) on the gait of patients with Multiple Sclerosis (MS).

Background TMS is a non-invasive neurophysiological technique that uses magnetic pulses, which act on the cerebral cortex, assisting neuromodulation. Furthermore, tDCS is also a non-invasive, safe and easy to apply technique, which is based on changes in the resting potential of the neuronal membrane. Both demonstrate results in terms of the patients' gait.

Design/Methods PubMed, LILACS and MedLine databases were used, with the descriptors “transcranial magnetic stimulation”, “transcranial direct current stimulation”, “multiple sclerosis” and “gait”. Longitudinal studies, such as case reports and clinical trials, that reported gait patterns before and after stimulation were included and literature reviews were excluded. There was no temporal cut due to the scarcity of the topic in the literature.

Results TMS significantly improves gait parameters. Regarding tDCS, physical exercise combined with stimulation appeared to enhance distances covered by patients. In a randomized clinical study with 17 participants divided into two groups, where the first group received tDCS plus physiotherapy and the second group received sham tDCS plus physiotherapy, the first group showed an average increase of 0,1 m/s in walking speed after 10 stimulation sessions. Furthermore, the experimental group achieved a reduction of 1,3 seconds in the TUG test. Regarding TMS, a case report in the literature demonstrated an increase of 0.25 m/s in a patient's walking speed after 9 stimulation sessions. In this study, a reduction of 3,4 seconds in the time to walk a distance of 6 meters was also observed.

Conclusions

TMS and tDCS have brought improvements in the gait of patients with MS. However, randomized studies with broader samples are needed to compare these techniques accurately, minimizing bias and guiding therapeutic choices.

Authors/Disclosures
Daniel V. De Siqueira Lima, Jr., MD PRESENTER	Dr. De Siqueira Lima has nothing to disclose.
BIANCA OLIVEIRA, MD (Horizon Therapeutics)	Dr. OLIVEIRA has nothing to disclose.
Yasmim Lisboa	No disclosure on file
Jamille Da Silva Abrantes	No disclosure on file
José Felipe Lacerda Fernandes	José Felipe Lacerda Fernandes has nothing to disclose.
Maria Donato Meneses Mendes	No disclosure on file
Maria Toscano Dos Santos	No disclosure on file
Tayane Medeiros Gomes	No disclosure on file
Fernando Melo Neto	No disclosure on file
ANA A. MEDEIROS	Mrs. MEDEIROS has nothing to disclose.
Thaís Magalhães Lima Leite	Mrs. Magalhães Lima Leite has nothing to disclose.
Cláudio Lima	No disclosure on file
Kaline Camelo	Kaline Camelo has nothing to disclose.
Sandra Gurgel	No disclosure on file
Artêmio José Araruna Dias, Sr. (Unifacisa)	Mr. Araruna Dias has nothing to disclose.

��ɫ��

��ɫ��