Abstract Details

Title Brain Cancer in the US: A Two Decade Study of Incidence Rates and Demographic Variations (1999-2021)

Topic Neuro-oncology

Presentation(s) P10 - Poster Session 10 (5:00 PM-6:00 PM)

Poster/Presentation
Number 6-011

Objective We aim to analyze trends in brain cancer incidence in the United States from 1999 to 2021.

Background Brain cancer makes up approximately 1% of the annual cancer diagnoses in the US, affecting the physical, psychological, and cognitive health of the American population. Assessing long-term trends is crucial to optimizing resource allocation and evaluating advances in diagnosis and treatment.

Design/Methods Brain cancer incidence data was extracted from the Centers for Disease Control and Prevention Wide-Ranging OnLine Data for Epidemiologic Research (CDC WONDER) database, focusing on age-adjusted incidence rates (AAIR) per 100,000 individuals. Annual Percent Changes (APC) were calculated using the Joinpoint Regression Software.

Results From 1999 to 2007, the overall brain cancer incidence plateaued at around 6.4 per 100,000. However, from 2007 to 2019, the incidence rate slightly declined to 6.0 (APC: -0.49% (95% CI: -0.62 to -0.36)). This decline continued and amplified between 2019 and 2021, reaching an incidence rate of 5.7 (APC: -2.70% (95% CI: -2.7 to -3.6)). Interestingly, during this period, brain cancer incidence advanced among American Indians, with an average APC of +0.9% (95% CI: 0.17 to 1.72).

The highest incidence rate was found in adults aged 80-84 years, at 21.4 per 100,000, with men overall showing higher rates (7.4) than women (5.22). Racial disparities were evident; non-Hispanic (NH) white individuals had the highest incidence rate at (7.0), followed by Hispanics (5.0), NH-American Indians (4.4), NH-Blacks (3.8), and NH-Asians (3.5). Regionally, the Northeast reported the highest incidence rates at (6.5), closely followed by the Midwest (6.4), South (6.1), and West (6.0).

Conclusions Overall, brain tumor incidence has shown a gradual decline since its peak in the early 2000s however rising incidence among NH-American Indians necessitates further investigation. Our research identified older adults, men, whites, and the northeast region to have the highest incidence rates.

Authors/Disclosures
Maryam Inam Zaroo, MBBS PRESENTER	Dr. Zaroo has nothing to disclose.
Muhammad Sohaib Khan	Mr. Khan has nothing to disclose.
Wania Moeen	Dr. Moeen has nothing to disclose.
Muzamil Khan, MBBS	Dr. Khan has nothing to disclose.
Wajeeh A. Khan	Dr. Khan has nothing to disclose.
Muhammad Jansher, MBBS	Mr. Jansher has nothing to disclose.
Waseem Nabi, MD	Dr. Nabi has nothing to disclose.
Reyan Hussain Shaikh, MBBS	Mr. Shaikh has nothing to disclose.
Mohammad Danish, MBBS	Mr. Danish has nothing to disclose.
Sakshi Roy, MBBS	Miss Roy has nothing to disclose.
Fariha Shariq, MBBS	Dr. Shariq has nothing to disclose.

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