Abstract Details

Title Use of Virtual Reality-based Exergames in Patients with Parkinson’s Disease: A Systematic Review and Meta-analysis

Topic Movement Disorders

Presentation(s) P11 - Poster Session 11 (8:00 AM-9:00 AM)

Poster/Presentation
Number 5-024

Objective This study aims to assess the efficacy of virtual reality-based exergames in improving motor symptoms among PD patients.

Background Parkinson's Disease is the most prevalent neurodegenerative disorder among older adults, with tremor, rigidity, and bradykinesia as its most common debilitating symptoms. Exergaming-based interventions have shown promising results in improving mobility and balance. However, uncertainty remains regarding their impact on motor symptoms, particularly in PD patients.

Design/Methods PubMed, Web of Science and Cochrane Library databases were searched for studies comparing exergames with usual approaches or conventional exercises, and reporting physical, psychological, or cognitive outcomes in PD patients. A random-effects model with a 95% confidence interval (CI) measured the mean difference (MD) and heterogeneity was examined with I² statistics. R software, version 4.4.1, was used for statistical analysis.

Results 23 RCTs and 811 patients were included, of which 328 (40.44%) underwent virtual reality-based exergames. No significant differences were found in motor symptoms measured by the Unified Parkinson's Disease Rating Scale-III (UPDRS-III) (MD -0.29; 95% CI [-2.92, 2.34]; P = 0.826; I² = 6%) or in the Timed Up and Go test (TUG) (MD -0.63; 95% CI [-1.49, 0.22]; P = 0.148; I² = 0%). However, significant improvements were observed in the Berg Balance Scale (BBS) (MD 1.43; 95% CI [0.43, 2.42]; P = 0.0049; I² = 49%), and in the Falling Efficacy Scale-International (FES-I) (MD -1.09; 95% CI [-1.98, -0.20]; P = 0.0167; I² = 38%).

Conclusions Our findings indicate that virtual reality-based exergames presented promising results associated with beneficial mobility improvement when compared to traditional physical training in PD patients.

Authors/Disclosures
Artur Menegaz de Almeida, MS PRESENTER	Mr. Menegaz de Almeida has nothing to disclose.
Hamilton Roberto Moreira de Oliveira Carrico	Mr. Roberto Moreira de Oliveira Carrico has nothing to disclose.
Carolina N. Calderoni, MS	Ms. Calderoni has nothing to disclose.
Andreza F. Amaral III, MS	Mrs. Amaral has nothing to disclose.
Carolina M. Vieira	Mrs. Vieira has nothing to disclose.
Larissa E. Tanimoto, student	Miss Tanimoto has nothing to disclose.
Pedro Henrique de Souza Wagner, Medical Student	Mr. DE SOUZA WAGNER has nothing to disclose.
Denisarth Oliveira Nery Filho, Sr., MS (Medical Student)	Mr. Oliveira Nery Filho has nothing to disclose.
Wingrid Raiane Barreto Goncalves Conceicão, MS	Miss Barreto Goncalves Conceicão has nothing to disclose.

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