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Abstract Details

Emboguard Balloon Guide Catheter in Stroke Thrombectomy: Procedural Insights and Outcomes
Cerebrovascular Disease and Interventional Neurology
P12 - Poster Session 12 (11:45 AM-12:45 PM)
13-020
To evaluate the performance of a newer-generation balloon guide catheter (Emboguard) in the treatment of anterior circulation large vessel occlusion.

Growing interest in optimizing endovascular thrombectomy (EVT) procedural techniques led to advancements in catheter technology and thrombectomy devices. Balloon guide catheters (BGC) facilitate proximal flow arrest and have demonstrated improved revascularization and functional outcomes.

A prospectively maintained EVT database was reviewed to identify all patients who underwent EVT using the Emboguard BGC. Outcomes included rates of complete and successful recanalization, number of passes, NIHSS at discharge, functional independence (mRS 0-2), favorable outcome (mRS 0-3), and mortality at 90 days. First-pass effect (FPE, mTICI 2c/3 after the first pass), modified-FPE (mTICI 2b-3 after the first pass), symptomatic intracranial hemorrhage, and mortality were evaluated.  

72 patients were identified. 56.94% were female, and the median age was 73 years [IQR 66.5-83]. The majority (88.9%) had middle cerebral artery (MCA) occlusion, with a median ASPECTS score of 9 [IQR 7-10]. Approximately 26.39% of patients received intravenous thrombolytics. Successful recanalization (mTICI 2b/3) was achieved in 98.61% (71/72) of cases, while complete recanalization (TICI 2c/3) occurred in 76.39% (55/72), with a median of 1 pass (IQR 1-2). FPE and modified-FPE were achieved in 48.61% and 56.94% of cases, respectively. The median NIHSS improved significantly from 17 (IQR 11-21) at baseline to 4 (IQR 1-12) at discharge. Symptomatic intracranial hemorrhage occurred in only 1 case (1.39%). At 90 days, functional independence (mRS 0-2) was achieved in 37.5%, favorable outcomes (mRS 0-3) in 57.14%, and mortality occurred in 25% of patients.

The Emboguard BGC showed promising results, demonstrating high rates of first-pass effect (FPE) and improved recanalization rates, all while maintaining a favorable safety profile. Prospective comparative studies are needed to validate these findings and further establish its efficacy in clinical practice.

Authors/Disclosures
Anmol Almast
PRESENTER
Miss Almast has nothing to disclose.
Bishow Chandra C. Mahat, MD (UPMC ME) Dr. Mahat has nothing to disclose.
Mohamed Fahmy Doheim (University of Pittsburgh) Mr. Doheim has nothing to disclose.
Vanessa Dwairi, MD Dr. Dwairi has nothing to disclose.
Abdullah M. Al-Qudah, MD (University of Pittsburgh Medical Center) Dr. Al-Qudah has nothing to disclose.
Lucas Rios Rocha, MD (UPMC) Dr. Rios Rocha has nothing to disclose.
Marcelo Rocha, MD, PhD (UPMC) The institution of Dr. Rocha has received research support from NIH.
Nirav Bhatt, MD (University of Pittsburgh) Dr. Bhatt has nothing to disclose.
Matthew T. Starr, MD (University of Pittsburgh Medical Center) Dr. Starr has nothing to disclose.
Michael Lang, MD Dr. Lang has nothing to disclose.
Bradley Gross, MD Dr. Gross has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Medtronic. Dr. Gross has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Microvention. Dr. Gross has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for AHA.
Raul G. Nogueira, MD (UPMC Stroke Institute) Dr. Nogueira has received personal compensation in the range of $50,000-$99,999 for serving as a Consultant for for advisory roles with Anaconda, Biogen, Cerenovus, Genentech, Hybernia, Imperative Care, Medtronic, Phenox, Philips, Prolong Pharmaceuticals, Stryker Neurovascular, Shanghai Wallaby, and Synchron (consulting fees) as well as for advisory roles with Astrocyte, Brainomix, Cerebrotech, Ceretrieve, Corindus Vascular Robotics, Vesalio, Viz-AI, RapidPulse and Perfuze ( stock options). Dr. Nogueira has received personal compensation in the range of $5,000-$9,999 for serving as an Expert Witness for Law Firms. Dr. Nogueira has received stock or an ownership interest from Viz-AI, Perfuze, Cerebrotech, Reist/Q'Apel Medical, Truvic, and Viseon. The institution of Dr. Nogueira has received research support from Cerenovus.
Alhamza Al-Bayati, MD (UPMC Stroke Institute) Dr. Al-Bayati has nothing to disclose.