Case Report:

A 6-year-old boy presented with concerns of multiple staring spells and was diagnosed with CAE following EEG evaluation. He was started on ethosuximide at a dose of 25 mg/kg/day divided BID. On the third day, he reported that his legs were cold, swollen and painful. Upon inspection mother reported clearly demarcated, white skin patches on bilateral feet and toes, confirmed on mom’s uploaded pictures, indicative of Raynaud's phenomenon. Ethosuximide was discontinued, and the symptoms resolved within two days with no intervention. He was exposed to no new medications recently, and ethosuximide remained his only medication. There was no familial history of autoimmune conditions.