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Abstract Details

Challenges in Recognizing Dermatological Findings of Dermatomyositis in Darker Skin patients: A Case Report
Autoimmune Neurology
P4 - Poster Session 4 (5:00 PM-6:00 PM)
8-015
NA
Dermatomyositis is a rare autoimmune myopathy, characterized by muscle fiber necrosis and inflammatory infiltrates in the perimysium, manifesting as proximal muscle weakness and myalgias. Dermatological findings are common, with characteristic heliotrope rash, Gottron papules, and poikiloderma. These findings are frequently missed in populations with darker skin tones, leading to increased time to diagnosis or misdiagnosis. 
NA

57 year old African-American female with prior medical history of hypertension, hyperlipidemia, asthma, and osteoarthritis presented to the hospital with four months of increasing muscle weakness and pain. She had previously been evaluated at a different hospital one month prior, after she lost the ability to ambulate without a walker, where she received no concrete diagnosis and had minimal improvement in her condition. Patient presented to our institution after she suffered from a fall due to worsening symptoms. Upon admission, it was noted that the patient had hyperpigmentation on the DIP and PIP joints consistent with Gottron papules, and facial hyperpigmentation, raising concern for dermatomyositis. Additional findings included bilateral upper and lower extremity weakness (proximal greater than distal), and work up showed leukopenia, elevated CK, highly positive ANA/RF. Thigh biopsy showing necrotic myofibers with foci of perifascicular atrophy, and positive HLA Class I immunohistochemistry. Over the course of admission, the patient was treated with steroids, IVIG, and mycophenolate mofetil, as well as daily PT sessions. Her symptoms gradually improved, with increased strength and independence in ambulation. Patient was discharged to a rehabilitation center with rheumatological follow up. 

Recognizing pathognomonic signs early in the course of disease can be critical in preventing long term complications and improving patient outcomes. Dermatological findings are frequently missed in patients with darker skin tones, underscoring the importance of thorough physical examinations and expanding medical education to expose physicians to a wide array of disease presentations. 
Authors/Disclosures
Iryna Mitelman, MD
PRESENTER
Dr. Mitelman has nothing to disclose.
Hesham Kelani, MD (One Brooklyn Health) Dr. Kelani has nothing to disclose.
Emina Dzafic Ms. Dzafic has nothing to disclose.
Srikanth Adidam Venkata, MD (SUNY Downstate At One Brooklyn Health - Brookdale Hospital) Dr. Adidam Venkata has nothing to disclose.
Selvalakshmi Rathinavelu, MD, MBBS (SUNY Downstate At One Brooklyn Health - Brookdale Hospital) Dr. Rathinavelu has nothing to disclose.
Nataly Mor, MD (SUNY Downstate At One Brooklyn Health - Brookdale Hospital) Nataly Mor, MD has nothing to disclose.
Helene Clervius, MD (SUNY Downstate At One Brooklyn Health - Brookdale Hospital) Dr. Clervius has nothing to disclose.
Artem Sunik, MD (Brookdale University Hospital Medical Center) Dr. Sunik has nothing to disclose.
Amit Khaneja, MD (Amit Khaneja Neurology Practice PLLC) Dr. Khaneja has nothing to disclose.
Arthur D. Kay, MD (Brookdale Hospital) Dr. Kay has nothing to disclose.
David P. Lerner, MD (One Brooklyn Health) Dr. Lerner has received publishing royalties from a publication relating to health care.
Lisa R. Merlin, MD, FAAN (SUNY Downstate Medical Center) Dr. Merlin has nothing to disclose.