Abstract Details

Title Exploring Bilateral Carpal Tunnel Syndrome in Underserved Communities: A Focus on AANHPI Populations and Risk Factors

Topic Neuromuscular and Clinical Neurophysiology (EMG)

Presentation(s) P4 - Poster Session 4 (5:00 PM-6:00 PM)

Poster/Presentation
Number 11-030

Objective Carpal tunnel syndrome (CTS) is a nerve condition caused by compression of the median nerve in the wrist.

Background This study addresses the limited research on CTS in Asian American, Native Hawaiian, and Pacific Islander (AANHPI) populations and compares their clinical presentation, comorbidities, and treatment with other racial groups in Hawaii.

Design/Methods This retrospective cohort study analyzed data from a neurological center in Hawaii. Adults (≥18 years) diagnosed with CTS between 2019-2023 were identified using ICD-10 codes. Patients without confirmed diagnosis via electromyography (EMG), clinical symptoms, or complete demographic data were excluded. Statistical analysis was performed using R, with significance set at p<0.05.

Results Data from 404 patients were analyzed: 35% were Native Hawaiian/Pacific Islanders (NHPI) and 33% were Asian. AANHPI patients had the highest rates of public insurance (p<0.001). NHPI patients had the highest obesity rates (p<0.001), while Asians had the lowest (p<0.001). Both Native Hawaiians and Asians had higher rates of hypertension (p=0.022, p=0.002), hyperlipidemia (p=0.042, p=0.020), and diabetes (p=0.008, p=0.021) compared to Whites. Native Hawaiians were also more likely to be smokers (p=0.003).

Conclusions AANHPI patients with CTS are more likely to rely on public insurance and present with comorbidities like hypertension, hyperlipidemia, and diabetes. NHPI patients, representing 18% of the county’s population, made up 35% of the CTS cases, with high rates of obesity and smoking. In contrast, Asians—who form 49% of the population—accounted for only 33% of CTS cases, were diagnosed later, and had the lowest obesity rates. These findings highlight the need to address comorbidities and reduce treatment disparities among AANHPI patients with CTS.

Authors/Disclosures
Ryan Nishi PRESENTER	Mr. Nishi has nothing to disclose.
Cadie Young	Ms. Young has nothing to disclose.
Ysabella A. Perez	Ms. Perez has nothing to disclose.
Anita Cheung, MPH	Miss Cheung has nothing to disclose.
D-Dré Wright	Ms. Wright has nothing to disclose.
Ryan Nakamura	Mr. Nakamura has received personal compensation for serving as an employee of Hawaii Health & Harm Reduction Center.
Kyle Ishikawa (University of Hawai'i)	Kyle Ishikawa has nothing to disclose.
Natalia Gonzalez Caldito, MD (home)	Dr. Gonzalez Caldito has nothing to disclose.
Enrique Carrazana (Neurelis, Inc.)	Enrique Carrazana has received personal compensation for serving as an employee of Neurelis. Enrique Carrazana has received personal compensation in the range of $10,000-$49,999 for serving as an officer or member of the Board of Directors for Hawaii-Biotech, CND Life Sciences, Apex Labs. Enrique Carrazana has stock in Neurelis, CND, Apex.
Kore K. Liow, MD, FACP (University of Hawaii, John Burns School of Medicine)	The institution of Dr. Liow has received research support from UCB. The institution of Dr. Liow has received research support from Livanova. The institution of Dr. Liow has received research support from Biogen. The institution of Dr. Liow has received research support from Novartis. The institution of Dr. Liow has received research support from Eisai. The institution of Dr. Liow has received research support from Engage Therapeutics. The institution of Dr. Liow has received research support from SK Lifescience. The institution of Dr. Liow has received research support from Cerevel. The institution of Dr. Liow has received research support from Xenon. The institution of Dr. Liow has received research support from NeuroDerm. The institution of Dr. Liow has received research support from Avanir. The institution of Dr. Liow has received research support from Annovis. The institution of Dr. Liow has received research support from Acadia. The institution of Dr. Liow has received research support from Prothena. The institution of Dr. Liow has received research support from SAGE. The institution of Dr. Liow has received research support from Annovis. The institution of Dr. Liow has received research support from Cyclerion.

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