Abstract Details

Title Stroke in Extracorporeal Membrane Oxygenation Patients: An Analysis from the National Inpatient Sample

Topic Cerebrovascular Disease and Interventional Neurology

Presentation(s) P6 - Poster Session 6 (11:45 AM-12:45 PM)

Poster/Presentation
Number 14-007

Objective To analyze the incidence and trends of these events in adult ECMO patients, and to investigate the association between age, gender, race, stroke occurrence, and mortality.

Background ECMO is a life-saving intervention for critically ill patients, but carries a risk of ischemic and hemorrhagic events, including stroke.

Design/Methods his retrospective study used NIS data (32,311 adult ECMO patients, 2004-2021). Event rates and trends were analyzed. Associations between age and stroke were evaluated using χ2 test and ANOVA. Logistic regression assessed the impact of various factors on mortality.

Results total 13.6 % ECMO patient had a stroke, 9.53% of pts had TIA or ischemic , 3.20% hemorrhagic, and 0.88% both. Ischemic events (100-176/yr) peaked in 2021 (235). Hemorrhagic events (21-46/yr) increased in 2020 (171) & 2021 (224). 13.6% had a stroke. Stroke incidence: 5.76% (18-34 yrs), 10.19% (35-49 yrs), 13.75% (50-64 yrs), 19.18% (65+ yrs) (χ2(3)=622.00, p=0.000). Pts with stroke were older (mean 61.69 yrs) vs. those without (mean 54.08 yrs) (F=715.25, p<0.0001). Mortality rates differed across stroke groups (F=156.36, p<0.001): no stroke (21.93%), ischemic (19.29%), hemorrhagic (48.01%), combined (42.29%). Hemorrhagic stroke (OR=2.75, p<0.001) & combined stroke (OR=1.69, p=0.001) increased mortality risk vs. ischemic stroke. Larger hospital size (OR=2.12 & 3.69 for size 2 & 3, p<0.005) & certain races (OR 1.60-1.93, p<0.01) also increased mortality. Age (OR=0.99, p=0.007) & LOS (OR=0.99, p=0.01) slightly reduced mortality.

Conclusions This study highlights the risk of ischemic and hemorrhagic events in adult ECMO pts, especially the rise in hemorrhagic events. Stroke type and age is a significant predictor of mortality, with hemorrhagic strokes increasing risk.

Authors/Disclosures
Muhammad Sohaib, MBBS PRESENTER	Mr. Sohaib has nothing to disclose.
Hafiz M. Maaz (Quaid-e-Azam Medical College, Bahawalpur Pakistan)	Mr. Maaz has nothing to disclose.
Muhammad Tayyab Muzaffar Chaychi, MD	Muhammad Tayyab Muzaffar Chaychi, MD has nothing to disclose.
Syed Haris Ahmed, MBBS	Dr. Ahmed has nothing to disclose.
Haris Kamal, MD (University of Texas At Houston)	Dr. Kamal has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Microvention .
Muhammad Ahmed, MD (Medical College of Georgia, Augusta University)	Dr. Ahmed has nothing to disclose.
Muhammad Tayyab Muzaffar Chaychi, MD	Muhammad Tayyab Muzaffar Chaychi, MD has nothing to disclose.

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