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Abstract Details

Unveiling the truth about Parkinson’s Disease Associated Dementia (PD-D) in the Black community
Aging, Dementia, and Behavioral Neurology
P6 - Poster Session 6 (11:45 AM-12:45 PM)
3-014

Determine the differences in rates of Dementia/ Atypical Parkinsonism between Black and White Parkinson’s Disease patients.
Parkinson's associated dementia (PD-D) is a condition that dramatically affects someone’s quality of life. While Parkinson's Disease impacts roughly 700,000 in the US, approximately 300-350,000 of these patients will develop PD-D or some other type of Atypical Parkinsonism.  The racial disparities between black and white PD-D patients are not extensively understood. The purpose of this study is to analyze the disparities in PD-D between White and Black Parkinson's Disease patients.
The Parkinson's Disease database (PD database) on REDCap was used to provide data for Dementia in Parkinson's Disease patients. A Chi-Square test analysis was performed in Excel to analyze the differences in rates of PD-D between Black and White Parkinson's Disease patients. A p-value was taken from the chi-square analysis with a 95% confidence interval. A  relative risk analysis was used to compare both groups for increased risk factors. A p-value was taken from the analysis with a 95% confidence interval.
We were able to show that Black Parkinson's Disease patients had a significantly higher chance of having a PD-D than White Parkinson's Disease patients (p-value=0.03155). 7.8% of Black Parkinson's Disease patients from the dataset have some variation of PD-D. Only 3.8% of White Parkinson's Disease patients have some variation of PD-D. The relative risk ratio for PD-D in Black Parkinson's Disease patients was between one to four (95% CI), indicating that Black Parkinson's Disease patients are two times as likely to have PD-D than White Parkinson's Disease patients.
These findings suggest that Black Parkinson's Disease patients are at a relatively higher risk of developing PD-D when compared to White Parkinson's Disease patients. This research may go on to show that Black Parkinson's Disease patients have more complicated cases of Parkinsonism than White patients.
Authors/Disclosures
Peter Daring, Morehouse School of Medicine
PRESENTER 		Mr. Daring has nothing to disclose.
Chantale O. Branson, MD, MSCR, FAAN (Morehouse School of Medicine) Dr. Branson has received personal compensation in the range of $0-$499 for serving on a Scientific Advisory or Data Safety Monitoring board for Supernus. Dr. Branson has received personal compensation in the range of $10,000-$49,999 for serving on a Scientific Advisory or Data Safety Monitoring board for UCB.