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Abstract Details

Marine Microplastics Levels and the Prevalence of Neurologic Disability
General Neurology
P8 - Poster Session 8 (8:00 AM-9:00 AM)
11-006

To investigate the correlation between marine microplastic levels in ocean water and the prevalence of cognitive, mobility, self-care, and independent living-associated disabilities in adjacent coastal counties.


Micro- and nanoplastics (MNPs) are recognized as emerging risk factors contributing to cognitive decline. However, the association between population-level marine microplastic levels (MMLs) and the prevalence of disabilities related to cognition, mobility, self-care, and independent living remains poorly understood. The study aims to investigate this association, exploring various proposed mechanisms for MNPs' impact on brain health and bridging the gap between environmental microplastic pollution and neurological disabilities.
In this cross-sectional study comprising 218 coastal counties in the United States, we compared the prevalence of cognitive disability, mobility disability, self-care disability, and independent living disability in counties with very high and low MMLs. Unadjusted and adjusted prevalence ratios (PRs) were computed using population-weighted quasi-Poisson regression across three different models to examine the relationship between disability prevalence and MMLs.

The mean prevalence of cognitive, mobility, self-care, and independent living disability was significantly higher in counties with very high MMLs (15.2%, 14.1%, 4.2% and 8.5%, respectively) compared to low MMLs (13.9%, 12.3%, 3.6% and 7.7%, respectively, p < 0.001). After adjusting for potential confounders, counties with very high MMLs showed significantly higher adjusted prevalence rate (PR) of cognitive (PR: 1.09 [1.06, 1.12], p < 0.001), mobility (PR: 1.06 [1.03, 1.10], p < 0.001), self-care (PR: 1.16 [1.11, 1.20], p < 0.001), and independent living disability (PR: 1.08 [1.05, 1.12], p < 0.001) compared to those with low MMLs.


Our findings indicate a significant association between marine microplastic levels and the prevalence of cognitive, mobility, self-care, and independent living disabilities in the US coastal counties. Further research is warranted to explore the potential public health implications of microplastic pollution.
Authors/Disclosures
Brinda Desai, MBBS
PRESENTER
Dr. Desai has nothing to disclose.
Bhargav Makwana, MD Mr. Makwana has nothing to disclose.
Jayashri Srinivasan, MD, PhD, MRCP, FAAN (Lahey Clinic) Dr. Srinivasan has nothing to disclose.
Diana Apetauerova, MD (Lahey Hospital and Medical Center) Dr. Apetauerova has nothing to disclose.
Sourbha S. Dani, MD Dr. Dani has nothing to disclose.
Siddharth Sehgal, MD (Lahey Medical Center) Dr. Sehgal has nothing to disclose.
Oleg Y. Yerstein, MD Dr. Yerstein has nothing to disclose.
Sumanth Khadke, MD Dr. Khadke has nothing to disclose.
Ashish Kumar, MBBS Dr. Kumar has nothing to disclose.
Khurram Nasir (Houston Methodist DeBakey Heart & Vascular Center) No disclosure on file
Rishi Wadhera, MD Dr. Wadhera has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Chamerbcardio. Dr. Wadhera has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Abbott. Dr. Wadhera has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for HSR Journal.
Yixin Kong, PhD Dr. Kong has nothing to disclose.
Ana Navas-Acien (Columbia University Mailman School of Public Health) No disclosure on file
Gary Adamkiewicz (Harvard T.H. Chan School of Public Health) No disclosure on file
sanjay rajagopalan, MD No disclosure on file
Sadeer G. Al-Kindi, MD Dr. Al-Kindi has nothing to disclose.
Susan D. Moffatt-Bruce, MD Dr. Moffatt-Bruce has nothing to disclose.
Sarju Ganatra, MD Dr. Ganatra has received personal compensation in the range of $500-$4,999 for serving as a Consultant for GLG. Dr. Ganatra has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Humana.