Residents completed a virtual communication scenario that involved consenting an aphasic patient (presenting with a large vessel occlusion (LVO)) and patient’s spouse for thrombolysis and thrombectomy. AI was used to simulate the patient’s spouse during this. The encounter was designed and delivered using the Yoodli™ platform. After residents completed the encounter, they were given feedback on their active listening skills, use of medical jargon, and review of medical contraindications to thrombolysis through Yoodli™. Residents then completed an in-person simulation encounter with a standardized patient presenting with a right middle cerebral artery (MCA) syndrome. Residents were tasked with obtaining a focused history, examining the standardized patient, interpreting CT head and CT angiography (depicting an LVO involving the right MCA), and consenting the standardized patient and acting spouse for thrombolysis and thrombectomy. A five-question feedback survey was distributed at the end of the simulation, assessing the utility of the AI communication encounter and feedback in practicing patient counseling.