Seven articles that discussed ocular manifestations in IgLON5 patients were found. Seven patients with IgLON5 disease reported in these articles were included in our analysis. The mean age of these seven patients was 61.7(±17.4) years. Six patients (85.7%) were male patients. Four patients (57.1%) presented with bilateral optic neuritis, while one with sixth nerve palsy, and one with limited horizontal pursuit eye movement. Additional symptoms included ataxia presented in three patients (42.9%) and cognitive impairment presented in four patients (57.1%). All patients had more than one clinical presentation. Six patients (85.7%) received at least one treatment, such as plasmapheresis, Intravenous immunoglobulin, or IV methyl prednisolone. Two patients (28.57%) experienced partial recovery, while five patients (71.43%) demonstrated complete recovery. Three patients (42.9%) were positive for cancer screening.