Abstract Details

Title Incidences and Characteristics of Repetitive Traumatic Brain Injury Between Sexual and Gender Minority Patients and Non-SGM Controls

Topic Neuro Trauma and Critical Care

Presentation(s) P1 - Poster Session 1 (8:00 AM-9:00 AM)

Poster/Presentation
Number 18-004

Objective To examine incidences and characteristics of repetitive traumatic brain injury (TBI) in patients who self-identified as sexual and gender minority (SGM), compared with non-SGM.

Background Recent evidence suggests SGM individuals are at increased risk of adverse neurological health outcomes. The impact of TBI on the SGM population remains underexplored.

Design/Methods Retrospective chart review of adult patients presenting with TBI to a United States Level 1 trauma center between 2019-2024. SGM patients were selected through the sexual orientation and gender identity SmartForm in Epic, and non-SGM patients were matched by year of presentation. The primary outcome was incidence of repetitive TBI, defined as a subsequent presentation for head injury within 5-years of the index TBI. Secondary outcomes were sociodemographic factors, TBI severity, and clinical outcomes.

Results 239 SGM and 271 non-SGM patients were identified. The incidence of repetitive TBI was higher in the SGM group vs. non-SGM (39% vs. 15%, p<0.0001). SGM patients were younger (median age 44 vs. 58-years, p<0.0001) and more likely to have history of psychiatric illness (68% vs. 29%, p<0.0001) and previous TBI (i.e., prior to the index TBI of inclusion, 31% vs. 20%, p=0.005). The majority of patients (n=348, 90%) had mild TBI (Glasgow Coma Scale score 13-15) and were discharged home (n=437, 86%). SGM patients differed in injury mechanisms, with fewer ground level falls (37% vs. 48%, p=0.009), more violence/assault (21% vs. 14%, p=0.048) and motorcycle/e-scooter accidents (8% vs. 3%, p=0.013).

Conclusions There was a considerably higher incidence of repetitive TBI within 5-years amongst SGM patients presenting with acute TBI compared with non-SGM. History of psychiatric illness, prior TBI, and TBI mechanisms of violence/assault and motorcycle/e-scooter accidents, were significantly higher in SGM patients. These findings underscore the distinct injury profile of SGM patients, and the critical need to identify specific risk factors to mitigate subsequent injury and improve outcome.

Authors/Disclosures
Dafna Erana Hernandez PRESENTER	Ms. Erana Hernandez has nothing to disclose.
Jaaie Varshney	Ms. Varshney has nothing to disclose.
Derby Gill	Ms. Gill has nothing to disclose.
David Castro (UCSF)	David Castro has nothing to disclose.
Sara Cole, RN (San Francisco General Hospital)	Ms. Cole has nothing to disclose.
John K. Yue, MD	The institution of Dr. Yue has received research support from University of California San Francisco Weill Neurohub. The institution of Dr. Yue has received research support from University of California San Francisco Weill Institute for the Neurosciences and University of California San Francisco Innovation Ventures Catalyst Award Grant.
H. E. Hinson, MD, MCR, FAAN (UCSF/Zuckerberg San Francisco General Hospital)	Dr. Hinson has received personal compensation in the range of $5,000-$9,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Neurology. Dr. Hinson has received personal compensation in the range of $5,000-$9,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for American Heart Association.
Nicole Rosendale, MD, FAAN (UCSF Dept of Neurology at ZSFG)	Dr. Rosendale has received personal compensation in the range of $5,000-$9,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Continuum. Dr. Rosendale has received personal compensation in the range of $10,000-$49,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for JAMA Neurology. The institution of Dr. Rosendale has received research support from ��ɫ��. The institution of Dr. Rosendale has received research support from NIH StrokeNet Fellowship. The institution of Dr. Rosendale has received research support from The Dana Foundation. The institution of Dr. Rosendale has received research support from UArizona-Banner All of Us Seed Grant. Dr. Rosendale has received publishing royalties from a publication relating to health care.
Michael Diaz, MD (UCSF)	Dr. Diaz has nothing to disclose.

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