Fifty studies comprising 74 patients (mean age: 34.47 years; 68% female) were analyzed. The pituitary gland was affected in 97% of cases and the pituitary stalk in 3%. The most frequent symptoms were headaches (55%) and visual impairment (47%). Magnetic resonance imaging (MRI) data were available for 48 patients and revealed suprasellar extension (73%), optic chiasm compression (46%), and pituitary stalk thickening (41%).
All patients received anti-tuberculosis therapy, mostly under an extended drug regimen. Surgery was performed in 69% of cases, predominantly via a transsphenoidal approach (64%). Following treatment, 55% of patients experienced visual improvement, and 89% achieved complete or near-complete clinical resolution. Postoperative diabetes insipidus occurred in 11% of cases. Other endocrine disturbances included hypocortisolism (14%), central hypothyroidism (12%), hyperprolactinemia (12%), and panhypopituitarism (11%). Approximately 19% of patients required long-term hormone replacement therapy. No mortality was reported among the 63 patients with available follow-up data.