Abstract Details

Title Neurological Outcomes in Cerebral Venous Sinus Thrombosis-an Observational Study

Topic Cerebrovascular Disease and Interventional Neurology

Presentation(s) P11 - Poster Session 11 (11:45 AM-12:45 PM)

Poster/Presentation
Number 4-017

Objective To determine cognitive outcomes in CVT in India.

Background Cerebral Venous Sinus Thrombosis (CVT) causes up to 15-20% of all stroke. In contrast to arterial strokes, CVT has better outcomes. In the International Study of CVT good outcomes (Modified Rankin Scale ≤2) were found in 86.5%.

Design/Methods This single centre observational cohort study was conducted in a tertiary care referral hospital in Western India, Pune from September 2022 to June 2025. Adult patients with imaging proven CVT were included. Cognition was assessed by Montreal Cognitive Assessment (MoCA) at 1 and/or 3 months.

Results A total of 59 CVT patients were studied with 44 (74.6%) males and mean age was 36.7 years. Aetiologies were hyperhomocystienemia (66.1%), alcohol (28.8%), connective tissue disorders (28.8%), smoking (20.3%), anaemia (25.4%), polycythaemia (13.5%), family history of CVT/DVT (11.8%) and OCP usage (11.8%). Intra cranial haemorrhage was present in 54.2%. Mean MoCA at 1 month was 21.7 and MoCA at 3 months was 23.15. Twenty-one patients had consecutive MoCA performed at 1 and 3 months with mean MoCA at 1 month 20.66 and Mean MoCA at 3 months was 22.57. A paired sample t-test revealed a significant difference p =0.03. Higher MoCA scores were found to correlate with higher education status (Pearson’s correlation r=0.67, p value <0.001); but not correlate significantly with lesser duration of hospital stay (r=-0.16, p value 0.25) and number of thrombosed sinuses (r= 0.14, p value 0.29).

Conclusions

Patients with CVT were found to have good neurological outcomes at one- and 3-month post CVT MoCA testing.

Authors/Disclosures
Sankar P. Gorthi, MD, FAAN (Bharati hospital) PRESENTER	Dr. Gorthi has nothing to disclose.
Dulari Gupta, MD, MBBS	Dr. Gupta has nothing to disclose.
Sreehari Dinesh, MD	Dr. Dinesh has nothing to disclose.
Pranav J. Mehta	Mr. Mehta has nothing to disclose.
Neha D. Mohite, Sr., MD	Dr. Mohite has nothing to disclose.

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