Abstract Details

Title Mortality Trends in Arrhythmia-associated Cerebrovascular Disease in Elderly Adults in the United States: A 25-Year Mortality Perspective

Topic Cerebrovascular Disease and Interventional Neurology

Presentation(s) P2 - Poster Session 2 (11:45 AM-12:45 PM)

Poster/Presentation
Number 5-019

Objective This study aims to investigate mortality trends in elderly adults in the United States specifically attributed to Arrhythmia-associated Cerebrovascular Disease (ACVD).

Background Arrhythmias are a group of cardiac disorders that disrupt normal heart conduction and can lead to serious complications, including cerebrovascular disease. Both conditions contribute significantly to morbidity and mortality in the elderly. However, national mortality trends specifically exploring this association (ACVD) have not been examined.

Design/Methods Data from CDC WONDER (1999–2023) was used to identify U.S. mortality rates in adults aged 65 and older where arrhythmias (ICD-10: I47-I49) and cerebrovascular disease (ICD-10: I60-I69) were listed as contributing or underlying causes of death. Age-adjusted mortality rates (AAMRs) per 100,000 were calculated. Joinpoint regression was utilized to estimate annual percent change (APC) and average annual percent change (AAPC).

Results Between 1999 and 2023, a total of 733,476 deaths among elderly adults (=65 years) were attributed to ACVD. The AAMR showed a slight upward trend from 72.14 in 1999 to 74.62 in 2023 (AAPC: 0.055, 95% CI: -0.62 to 0.74), with a significant increase from 65.51 in 2018 to 80.44 in 2021 (APC: 6.65). Men had higher AAMR than women during 1999-2023 with (73.97 to 81.27 vs 70.22 to 69.2). Non-Hispanic White individuals had the highest AAMR in 2021 (87.43) and the largest total number of deaths (631,483). The South recorded the most deaths (251,478). Non-metropolitan areas consistently had higher AAMRs compared to metropolitan areas (73.62 vs. 64.71). The majority of deaths occurred in inpatient medical facilities (38.73%, 284,079 deaths).

Conclusions Mortality from Arrhythmia-associated Cerebrovascular Disease has shown an increasing trend in the elderly U.S. population, with disparities by sex, race, and region. Most deaths occur in inpatient facilities, highlighting intervention needs.

Authors/Disclosures
Mohamed F. Hemida Saleh PRESENTER	Dr. Hemida Saleh has nothing to disclose.
Alyaa Ahmed Ibrahim, MBBS (Alexandria Faculty of Medicine)	Dr. Ibrahim has nothing to disclose.
Maryam Saghir, MBBS	Miss Saghir has nothing to disclose.
Mahmoud Tablawy, MD	Dr. Tablawy has nothing to disclose.
Ahmed Hamza, MD	Mr. Hamza has nothing to disclose.
Alaa El-Deeb, MD	Dr. El-Deeb has nothing to disclose.
Sahil Jairamani	Dr. Jairamani has nothing to disclose.
Eshal Saghir, MBBS	Miss Saghir has nothing to disclose.
Pakeezah Tabasum	Miss Jokhio has nothing to disclose.
Ahmed Ebrahim, MD	Dr. Ebrahim has nothing to disclose.
Amro Ali, MD	Dr. Ali has nothing to disclose.

��ɫ��

��ɫ��