Abstract Details

Title Comparing Psychopathologies Between Anorexia Nervosa-restricting (AN-R) and Binge-eating/Purging (AN-BP) Subtypes

Topic General Neurology

Presentation(s) P2 - Poster Session 2 (11:45 AM-12:45 PM)

Poster/Presentation
Number 7-006

Objective To compare the psychopathological features of the AN-R and AN-BP subtypes among individuals with active anorexia nervosa (AN).

Background AN is a life-threatening eating disorder characterized by two clinical subtypes: restricting (AN-R) and binge-eating/purging (AN-BP).

Design/Methods We administered the Eating Disorder Inventory (EDI-3) and Eating Disorder Examination Questionnaire (EDE-Q) to adult women currently ill with AN. Participants were classified by subtype (AN-R or AN-BP). Mann–Whitney U tests were conducted using RStudio to compare subscale and composite scores between subtypes.

Results

Participants (n=54) had a mean age of 30.7 ± 11.1 years and a mean BMI of 16.7 ± 2.4. The AN-BP group (n = 29) exhibited significantly greater severity than the AN-R group (n = 25) on several EDI-3 subscales: Bulimia (12.69 ± 8.37 vs. 3.80 ± 5.69, p < 0.005), Personal Alienation (16.87 ± 6.32 vs. 12.45 ± 6.76, p = 0.049), Emotional Dysregulation (8.79 ± 6.21 vs. 5.97 ± 6.87, p = 0.044), and Maturity Fears (12.28 ± 6.27 vs. 9.32 ± 6.95 vs, p = 0.049); as well as two EDE-Q subscales: Restraint (3.79 ± 1.75 vs. 2.68 ± 1.76 ; p = 0.028) and Shape Concern (4.51 ± 1.39 vs. 3.45 ± 1.99, p = 0.041) (Mean ± SD; AB-BP vs. AN-R, respectively).

Conclusions Distinct psychopathological profiles differentiate the AN-R and AN-BP subtypes. Elevated impulsivity and affective symptoms in AN-BP warrant interventions addressing both impulse control and emotion regulation. These findings underscore the heterogeneity of AN and the importance of subtype-specific treatment approaches. Moreover, neurobiological mechanisms underlying AN may contribute to impaired cognitive flexibility and maladaptive behaviors. Therefore, rigorous neurobiological research is needed to identify novel approaches for improving treatment and outcomes.

Authors/Disclosures
Nhi N. Nguyen, MA PRESENTER	Ms. Nguyen has nothing to disclose.
Kimberly Nguyen	Ms. Nguyen has nothing to disclose.
Ha T. Nguyen, Data Reviewer	Mrs. Nguyen has nothing to disclose.
Xia Wu, MBBS	Mrs. Wu has nothing to disclose.
Blake Woodside (University of Toronto)	No disclosure on file
Pei-an Betty Shih, PhD	The institution of Dr. Shih has received research support from NIH.

��ɫ��

��ɫ��