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Abstract Details

Identifying Barriers to Medications Adherence and Outpatient Follow-up After Transient Ischemic Attack: A Cross-sectional study
Cerebrovascular Disease and Interventional Neurology
P3 - Poster Session 3 (5:00 PM-6:00 PM)
5-006
To evaluate adherence to secondary stroke prevention medications (antiplatelet and/or statin) and outpatient follow-up after TIA discharge, along with identifying barriers to noncompliance and loss to follow-up.
Adherence to secondary stroke prevention and timely outpatient follow-up is essential to reduce the risk of subsequent stroke following a TIA. However, reasons for medication noncompliance or loss of follow-up remains poorly understood. 
We conducted a survey of patients discharged after TIA (April 2024–2025) evaluating compliance with antiplatelet and statin therapy, rate of outpatient follow-up, and reasons for noncompliance or loss to follow-up. Understanding of diagnosis and rationale behind medications was measured with a 3-point Likert scale. Demographic data were collected retrospectively. Logistic regression with Fisher’s exact tests identified predictors of follow-up. 

Of 88 eligible patients, 66 (75%) completed the survey. Noncompliance with antiplatelet and/or statin therapy occurred in 24.2% (n=16), while 19.7% (n=13) were lost to follow-up. Reported reasons for noncompliance included belief medication was not necessary (25%), side effects without physician input (18.7%), physician-advised discontinuation (18.7%), and forgetfulness (12.5%). Among those lost to follow-up, 76.9% felt follow-up was not necessary and 23.1% cited insurance barriers. Regarding understanding, 10.6% disagreed and 22.7% somewhat agreed with “I understand my diagnosis of TIA.” For medication rationale, 21.1% somewhat agreed and none disagreed with “I understand the rationale for prescribed stroke prevention medications.”  

Medication-compliant patients were likely to attend outpatient follow-up (OR 6.17; 95% CI: 1.56–24.42; p<0.005), while other demographic data and cardiovascular risk factors were not significantly associated with compliance. 

About one in five TIA patients were non-adherent to secondary prevention medication or lost to follow-up, most often because patients decided it was not needed. Nearly one-third reported limited understanding of their diagnosis, highlighting the need for improved methods for patient counseling. Study limited by a small sample size.
Authors/Disclosures
Chetna Dengri, MD
PRESENTER
Dr. Dengri has a non-compensated relationship as a Trainee board member with Neurology 好色先生 Journal Editorial Board that is relevant to AAN interests or activities.
Muaz Ali, MD Dr. Ali has nothing to disclose.
Paola V. Oyola Miss Oyola has nothing to disclose.
Amre Nouh, MD, FAAN (Cleveland Clinic) Dr. Nouh has stock in Openwater.