Abstract Details

Title Coproduced Adaptation of a Remotely Delivered Psychoeducation Program to Improve Quality of Life and Cognition in Adults With Multiple Sclerosis: Feasibility and Acceptability Pilot

Topic Neuro-rehabilitation

Presentation(s) P4 - Poster Session 4 (8:00 AM-9:00 AM)

Poster/Presentation
Number 14-011

Objective To adapt and evaluate the feasibility and acceptability of a remotely delivered self-management program for adults with multiple sclerosis (MS) and cognitive dysfunction.

Background Cognitive dysfunction and reduced quality of life (QoL) are common in MS. The psychoeducation program called HOBSCOTCH (HOme Based Self-Management and COgnitive Training CHanges Lives), originally developed for epilepsy, has shown efficacy in improving QoL and subjective cognition. This efficacy has prompted systematic adaptation of HOBSCOTCH to address care gaps in other neurologic conditions, including MS. We describe a telehealth adaptation for MS and its pilot evaluation.

Design/Methods Program design was informed using Community Engagement Studio (CES) methodology involving adults with MS and by input from the National MS Society. Qualitative feedback identified priorities for the adapted curriculum, including: (1) flexible scheduling; (2) one-on-one delivery; (3) participant-driven format; (4) emotion-regulating resources; (5) education on cognition in MS; (6) mindfulness instruction; (7) inclusion of care partners; and (8) visibility within the MS community. Post-CES, a feasibility and acceptability pilot of HOBSCOTCH-MS was conducted. QoL (FAMS), subjective cognition (NeuroQOL), and satisfaction were assessed.

Results At baseline, pilot participants (n=8) reported mediocre QoL (M=106.88, SD=23.29) and considerable cognitive deficits (M=42.65, SD=7.69). Qualitative pilot outcomes demonstrated strong feasibility and acceptability. All pilot participants who completed the program (n=8) attended every session, completed homework, and responded "very" or "extremely" regarding their satisfaction with the coach-participant relationship and their likelihood of recommending the program. Participants responded "moderately" (25%), "very” (12.5%), or "extremely" (62.5%) regarding the usefulness of learned strategies and their likelihood of applying program skills to everyday life.

Conclusions Coproduction with the MS community facilitated adaptation of a remotely delivered psychoeducation program for people with MS. Pilot findings have informed an ongoing randomized-controlled efficacy trial of the adapted HOBSCOTCH-MS intervention; primary outcomes in 125 patients enrolled from 2025-2028 will include QoL and subjective cognitive function.

Authors/Disclosures
Audrey L. Herrald PRESENTER	Miss Herrald has nothing to disclose.
Tiffany L. Israel, MSSW	Ms. Israel has received personal compensation for serving as an employee of VentureWell. The institution of Ms. Israel has received research support from PCORI. The institution of Ms. Israel has received research support from CDC. The institution of Ms. Israel has received research support from NIH. Ms. Israel has received personal compensation in the range of $500-$4,999 for serving as a Consultant with Dartmouth. Ms. Israel has received personal compensation in the range of $500-$4,999 for serving as a Consultant with University of Pennsylvania.
Sarah J. Kaden, BA	Mr. Kaden has nothing to disclose.
Heather Wishart, PhD	The institution of Dr. Wishart has received research support from National MS Society, DoD MS and Brain Tumor Research Programs, VA, and National Cancer Institute. Dr. Wishart has received personal compensation in the range of $0-$499 for serving as a Grant Reviewer with Hitchcock Foundation.
Barbara C. Jobst, MD, PhD, FAAN (Dartmouth-Hitchcock Med Ctr)	Dr. Jobst has received personal compensation in the range of $10,000-$49,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for AAN. The institution of Dr. Jobst has received research support from Neuropace, Inc.. The institution of Dr. Jobst has received research support from NIH. The institution of Dr. Jobst has received research support from CDC.
Elaine T. Kiriakopoulos, MD (Dartmouth-Hitchcock Medical Center)	The institution of Dr. Kiriakopoulos has received research support from Centers for Disease Control and Prevention. The institution of Dr. Kiriakopoulos has received research support from Department of Defense. The institution of Dr. Kiriakopoulos has received research support from Epilepsy Foundation New England.

��ɫ��

��ɫ��