Abstract Details

Title Personality Disorders in Patients with Idiopathic Generalized Epilepsy – An Under-recognized Folie!

Topic Epilepsy/Clinical Neurophysiology (EEG)

Presentation(s) P6 - Poster Session 6 (5:00 PM-6:00 PM)

Poster/Presentation
Number 10-006

Objective We aimed to explore the prevalence and types of personality disorders in persons with IGE and to compare it with the general population.

Background Personality disorders remain as an illness in the shadows, with scarce literature on their prevalence in people with epilepsy. Moreover, personality disorders in idiopathic generalized epilepsy (IGE) have not been explored so far. While previous studies have focused on Juvenile Myoclonic Epilepsy, we aimed to assess whether similar patterns extend to other IGE subtypes and to compare their prevalence as well as explore pattern of various types of personality disorders with respect to general population.

Design/Methods We included 57 healthy controls and 57 IGE cases who were diagnosed according to the International League Against Epilepsy criteria. The IPDE-ICD10 screening questionnaire was employed to investigate personality disorders, while the Bear-Fedio inventory (BFI) was utilized to study several behavior traits.

Results Compared with controls, a higher prevalence of personality disorders was noted among patients with IGE (87.72% versus 36.84%, p=<0.001). They were more prevalent in female patients with IGE as compared to males (96.97% versus 75%; p=0.034). Personality traits like borderline(p=<0.001), anankastic(p=<0.001), anxious(p=<0.001), histrionic(p=<0.001), and impulsive(p=0.002) were higher in patients with IGE. Significantly higher scores in BFI were found among cases in all behavioral traits except hyper moralism, altered sexual, and dependence traits. Personality disorders were higher among female patients with IGE .On further analysis no association with the number of antiseizure medications nor the duration of epilepsy was seen for personality disorders.

Conclusions Personality disorders were significantly higher in patients with IGE. Regardless of the subtype, the existence of a personality disorder makes treatment challenging. Hence, specific interventions addressing these disorders should be incorporated in patient management.

Authors/Disclosures
Ankith Bhasi, MD, DM PRESENTER	Dr. Bhasi has nothing to disclose.
Bharanidharan Gurumurthy, MD, DM	Dr. Gurumurthy has nothing to disclose.
Ramshekhar N. Menon, MD, MBBS, DM; PDF (Neurology Dept, Sree Chitra Tirunal Institute for Medical Sciences & Technology)	Dr. MENON has nothing to disclose.
Ashalatha Radhakrishnan, Sr., MD (Sree Chitra Tirunal Institute for Medical Sciences & Technology)	Dr. Radhakrishnan has nothing to disclose.

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