We conducted a retrospective chart review of genetically confirmed DMD patients seen at a single institution between 2015-2025. Patients with less than one year of follow-up, fewer than 2 visits, or unrelated comorbidities affecting fracture risk were excluded. Data on LBF, FES, mechanism of injury, ambulatory status, duration of steroid use, and bisphosphonate therapy were collected. Association between LBF, steroid exposure, and ambulatory status was analyzed using Cox regression model.

LBFs are common in DMD often following a minor trauma, posing a substantial risk for FES resulting in irreversible decline and high mortality. This is the first study identifying FES incidence in a single center cohort underscoring the need for vigilant bone health monitoring and early preventive interventions in this high-risk population.