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Abstract Details

Validation of a Neuropsychological Test Battery for Detecting Mild Cognitive Impairment and Alzheimer's Disease in an Elderly Lebanese Population
Aging, Dementia, and Behavioral Neurology
P7 - Poster Session 7 (8:00 AM-9:00 AM)
13-012

This study aims to evaluate the effectiveness of several neuropsychological tests in detecting Mild Cognitive Impairment (MCI) and Alzheimer’s Disease (AD) among Lebanese Arabic-speaking individuals.

In Arabic-speaking countries, including Lebanon, the lack of culturally validated neuropsychological assessment tools complicates the differentiation between normal cognitive aging, MCI, and AD.

A battery of cognitive assessments was administered, including the Mini-Mental State Examination (MMSE), Modified Mini-Mental State (3MS), Montreal Cognitive Assessment (MoCA), Brief Visuospatial Memory Test-Revised (BVMT-R), Digit Span, and Verbal Fluency tests. Participants were divided into control, MCI, and AD groups. Sensitivity, specificity, and diagnostic accuracy were evaluated for each test.

The MMSE and MoCA were effective in identifying AD, though MoCA’s sensitivity for MCI was lower than expected. The 3MS demonstrated a good balance between sensitivity and specificity, making it a valuable tool for distinguishing between MCI and AD. The BVMT-R and Digit Span showed limitations, with BVMT-R being less effective in distinguishing MCI from normal controls and Digit Span having low sensitivity for MCI but good specificity for AD.

Our findings suggest that the 3MS, in combination with other cognitive tests, is a reliable tool for screening MCI and AD in Lebanon. While these results are consistent with international standards, further validation with a broader population is necessary to improve generalizability. This study advances the development of culturally adapted cognitive assessments, emphasizing the need to consider cultural factors in neuropsychological evaluations.

Authors/Disclosures
Fadi K. Abou-Mrad, MD, PhD, FAAN (St Charles Hospital-Fayadieh)
PRESENTER
Dr. Abou-Mrad has nothing to disclose.
Tatiana Abou Mrad, MD Dr. Abou Mrad has nothing to disclose.
PATRICIA P. FADEL, Sr., MD Dr. FADEL has nothing to disclose.
Maryse E. Hayek, PhD Dr. Hayek has nothing to disclose.
Lubna Tarabey, PhD Prof. Tarabey has nothing to disclose.