Abstract Details

Title Trends and Disparities in Hypertension and Dementia Related Mortality in the United States: A Nationwide Analysis Using CDC WONDER Data, 1999–2023

Topic Global Health and Neuroepidemiology

Presentation(s) P7 - Poster Session 7 (8:00 AM-9:00 AM)

Poster/Presentation
Number 20-009

Objective To analyze hypertension (HTN) and dementia related mortality trends stratified by gender, age, race, region, and place of death within the United States (US) from 1999–2023.

Background HTN is an established risk factor for cognitive decline and subsequent dementia development; however, concomitant mortality trends of HTN and dementia remain understudied in the US.

Design/Methods We analyzed CDC WONDER Database for mortality data of 25+ years individuals using ICD-10 codes for dementia (G30, G31, F01, F03) and HTN (I10). Age-adjusted mortality rates (AAMR) per 100,000 and annual percentage changes (APCs) were computed using the Joinpoint Regression Program. Results were statistically significant if p-value <0.05 (indicated by *).

Results From 1999–2023, there were 1,388,390 deaths attributed to HTN and dementia. Overall, AAMR increased sharply from 4.16 to 15.5 between 1999 and 2001 (APC = 76.48*), followed by a significant rise to 31.9 in 2023 (APC = 2.44*). Females (26.2) had a higher AAMR than males (20.3). A notable increase was observed across all age groups, particularly 65–74 years (2001–2023 APC = 3.23*) and 85+ years (2001–2023 APC = 2.46*). Non-Hispanic (NH) Blacks had the highest AAMR (32.76), followed by NH Whites (24.16), Hispanics (19.26), NH American Indians/Alaskan Natives (19.24), and NH Asians/Pacific Islanders (14.75), with a significant mortality rise among NH Whites (2001–2023 APC = 2.72*). Regional AAMR variations were observed (South= 26.41, Midwest=25.58, West=24.19, Northeast= 18.64), with a consistent mortality incline across all regions, particularly the South (2001–2023 APC = 3.05*). Nursing homes and long-term care facilities accounted for 53.71% of total deaths.

Conclusions The aforementioned disparities can help identify the high-risk groups and require targeted public health interventions for managing HTN and dementia within the US.

Authors/Disclosures
Syeda Alisha Johar, MD PRESENTER	Dr. Johar has nothing to disclose.
Rana Faheem U. Khan, MBBS	Dr. Khan has nothing to disclose.
Hadiya Javed, MBBS	Ms. Javed has nothing to disclose.
Syeda Rabiah Shahid, MBBS	Dr. Shahid has nothing to disclose.
Ezza Bashir, MD	Dr. Bashir has nothing to disclose.

��ɫ��

��ɫ��