A retrospective observational study reporting patients with post-stroke seizures from a tertiary care teaching institute in India.

Stroke is a major cause of seizures in elderly patients; however there is a lack of sufficient data from our country. Post-stroke seizures may require life long treatment causing a significant burden of care in patients residing in third world countries.

In our cohort of 35 patients with stroke-related seizures, 10 were female (28.5%) and mean age was 68.7 ± 11.8 years. Out of 35 patients, 28 (80%) had ischemic lesions, 5 (14.2%) had hemorrhagic lesions and 2 patients (5.7%) had both. Patients with chronic infarcts were the major bulk of the cohort (57.1%) amongst which 9 (25.7%) had focal infarcts and 11 (31.4%) had multifocal lesions. 6 patients (17.1%) had acute ischemic stroke, all of them were multifocal. 2 patients (5.7%) had both acute and chronic infarcts. 5 (14.2%) patients had chronic hemorrhage out of which, 3 had focal lesions (8.5%) and 2 had multifocal involvement. Cortical involvement predominated in our study with most patients having lesions in parietal (51.4%) and occipital (40%) lobes, followed by frontal (28.5%) and temporal (25.7%) cortices. Subcortical and infratentorial structures were involved in <20% of the patients. Left and bilateral lesions slightly outnumbered right only involvement.

Ischemic, chronic, multifocal and cortical lesions were strongly associated with post stroke seizures in our cohort.