Abstract Details

Title Association Between Hemoglobin Levels and Hemorrhagic Stroke Outcomes: A Cross-sectional Study on Recovery and Prognosis

Topic Cerebrovascular Disease and Interventional Neurology

Presentation(s) P9 - Poster Session 9 (5:00 PM-6:00 PM)

Poster/Presentation
Number 4-011

Objective The objective is to evaluate the association between hemoglobin levels and hemorrhagic stroke outcomes in order to evaluate recovery and prognosis in these patients.

Background Abnormal hemoglobin may influence cerebral blood flow and oxygen delivery, which is a risk factor for stroke recovery. Although anemia and polycythemia are associated with outcomes, no evidence is clear on the subject. We assessed the correlation of Hb, HS severity and outcomes.

Design/Methods A cross-sectional study was conducted among adults with acute hemorrhagic stroke. Hemoglobin within 24 h was classified as low (<12 g/dL females, <13 g/dL males), normal, or high. Stroke severity was measured by NIHSS and outcomes by mRS at discharge. Baseline traits were summarized descriptively. Group differences used Pearson χ² with Cramér’s V, Mann–Whitney U, or Kruskal–Wallis. Multivariable logistic regression identified predictors of favorable outcome (mRS 0–2) and mortality. Model fit used Hosmer–Lemeshow and Nagelkerke R².

Results

A total of 445 patients (Hb-low 330 [74.2%], normal 114 [25.6%], high 1) were included; Baseline severity and outcomes were similar by Hb group (NIHSS 9.74 ± 7.02 vs 10.64 ± 6.25; mRS 2.15 ± 2.20 vs 2.25 ±1.78) with deaths [32/330 (9.7%) vs.C >4/114 (3.5%]. Higher mRS(p<0.0001) and mortality were related to later arrival (p=0.013). Diabetes(p<0.001), hypertension (p=0.0001) and age (p = 0.0049) predicted poorer outcomes. There was no difference in mRS(p=0.257) or NIHSS (p=0.245) according to Hb category. In multivariable models, Hb was not an independent predictor of outcome/death; NIHSS remained the dominant predictor (favorable outcome:aOR 0.77 per point, p<0.001; mortality: aOR 1.07 per point, p=0.019), with diabetes also increasing death risk (aOR 2.58, p=0.014).

Conclusions Hemoglobin was not independently correlated with hemorrhagic stroke recovery, prognosis or mortality. Stroke severity and history of diabetes were independent predictors of poor outcome. Routine hemoglobin screening is still clinically relevant, but trageted correction may not translate to better recovery.

Authors/Disclosures
Dhyey Sidhpura, MD PRESENTER	Dr. Sidhpura has nothing to disclose.
Ayesha Johar, MD	Dr. Johar has nothing to disclose.
Faraz Ahmad	Dr. Ahmad has nothing to disclose.
Javeria M. Akhter, MSPH	Miss Akhter has nothing to disclose.
Huzaifa S. Nawaz, MBBS	Dr. Nawaz has nothing to disclose.
Wajiha Aftab, Undergraduate MBBS student	Ms. Aftab has nothing to disclose.
Maham Jawad, MBBS	Dr. Jawad has nothing to disclose.
Syeda U. Tirmizi	Dr. Tirmizi has nothing to disclose.
Soma Khalid (Shaheed Mohtarma Benazir Bhutto Medical College Lyari)	No disclosure on file
Sameen Fida, MBBS	Dr. Fida has nothing to disclose.

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