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Abstract Details

Understanding Diagnostic Pathways and Barriers to Care for Patients Presenting with Suspected Acute Stroke in Lusaka, Zambia
Cerebrovascular Disease and Interventional Neurology
P6 - Poster Session 6 (5:00 PM-6:00 PM)
2-013

To characterize delays in evaluation and inter-facility transfer among patients presenting with suspected acute stroke at first-level hospitals in Lusaka, Zambia.

Stroke is a leading cause of death among adults in Zambia. Even when patients arrive within clinically meaningful time windows, in-hospital delays in care can eliminate eligibility for time-sensitive interventions and contribute to complications and mortality. Understanding diagnostic and transfer pathways at first-level facilities is essential to strengthening regional stroke systems of care.

We conducted structured observations of consecutive patients presenting with stroke-like symptoms at four first-level hospitals in Lusaka (July to November 2025). Observers followed patients from arrival through triage, initial stroke evaluation (defined as the first clinical assessment with documented neurologic exam or explicit stroke consideration), early management steps, consultation with higher-level care, and disposition decision (admission, transfer, discharge, or death). Descriptive statistics are reported.

A total of 52 patients with suspected stroke were observed. Twenty (38%) arrived within 4.5 hours of last known well, including 16 (31%) within 3 hours. Transport to first-level hospitals occurred primarily via private vehicle (n=23) or taxi (n=18); ambulance transport was uncommon (n=3). Clinical stroke evaluation was frequently delayed or absent: 4% (2/52) had no documented stroke evaluation during observation; among those evaluated (50/52), 40% (20/50) were evaluated >30 minutes after arrival, and 20% (10/50) were evaluated >5 hours after arrival. None of the first-level facilities had computed tomography capability; no patients underwent head CT before disposition decisions were made. Twelve patients (23%) were transferred to a higher-level facility, all by ambulance, and transfers were also frequently delayed. Among transferred patients, the decision-to-departure time (from decision to transfer to ambulance departure) had a mean of 5 hours 19 minutes and median of 4 hours 45 minutes.

A substantial fraction of suspected stroke patients presenting to first-level hospitals in Lusaka arrive within potential treatment windows. However, delays in early clinical evaluation and inter-facility transfer may prevent timely access to definitive stroke care. These findings highlight actionable targets for stroke pathway redesign, triage standardization, and strengthened inter-facility transfer coordination. Interventions targeted at these bottlenecks, such as rapid tele-neurology-supported stroke triage and expedited transfer protocols, warrant evaluation in this setting. Mobile stroke unit strategies may be considered where feasible.

Authors/Disclosures
Gabriel Sneh, MD (Johns Hopkins)
PRESENTER
Dr. Sneh has nothing to disclose.
Madalitso Nthere, MBBS Dr. Nthere has nothing to disclose.
Lyambula D. Lyelu, MD Dr. Lyelu has nothing to disclose.
Emmanuel Mukambo, MD Dr. Mukambo has nothing to disclose.
Diwell Mwansa (UNZA Ridgeway campus) Diwell Mwansa has nothing to disclose.
William Tembo, MD An immediate family member of Mr. Tembo has received research support from City University of New York (CUNY).
Deanna Saylor, MD, MHS (Johns Hopkins Hospital) Dr. Saylor has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for 好色先生. The institution of Dr. Saylor has received research support from National Institutes of Health. The institution of Dr. Saylor has received research support from 好色先生. Dr. Saylor has a non-compensated relationship as a Member of multiple committees and task forces focused on improving access to MS medications to people across the world with Multiple Sclerosis International Federation that is relevant to AAN interests or activities. Dr. Saylor has a non-compensated relationship as a Member of the Neurology and COVID19 committee with World Health Organization that is relevant to AAN interests or activities. Dr. Saylor has a non-compensated relationship as a Member of the International Outreach Committee, Junior and Early Career Membership Committee, and 好色先生al Innovation Commitees with American Neurological Association that is relevant to AAN interests or activities.