好色先生

好色先生

Explore the latest content from across our publications
Join The AAN

Log In

Forgot Password?
Create New Account

Loading... please wait

Abstract Details

Myositis-specific Antibody Testing: Methods Matter!
Autoimmune Neurology
P2 - Poster Session 02 (3:00 PM-4:00 PM)
1-018

Evaluate the recently developed particle-based multi-analyte technology (PMAT) assay for the detection of MSA in comparison to line immunoblot assay (LIA), multiplex bead assay (MBA), and/or immunoprecipitation (IP).

Myositis-specific antibodies (MSA) represent important diagnostic tools for people with inflammatory muscle disease. Variability in testing methods between labs can result in challenges for clinicians interpreting these results. IP remains the gold standard, but other assays offer antigen-specific testing with simplified laboratory methods.

Myositis-specific antibodies (MSA) represent important diagnostic tools for people with inflammatory muscle disease. Variability in testing methods between labs can result in challenges for clinicians interpreting these results. IP remains the gold standard, but other assays offer antigen-specific testing with simplified laboratory methods.

We report on the frequency of detection of MSA in a reference laboratory setting, including the agreement between PMAT, IP, LIA, and/or MBA. We describe the clinical characteristics of University of Utah patients positive for MSA using these methods.

We report on the frequency of detection of MSA in a reference laboratory setting, including the agreement between PMAT, IP, LIA, and/or MBA. We describe the clinical characteristics of University of Utah patients positive for MSA using these methods.
Authors/Disclosures
Lisa K. Peterson, PhD (ARUP Laboratories)
PRESENTER 		Dr. Peterson has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Werfen. Dr. Peterson has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Werfen. Dr. Peterson has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for AliveDx. Dr. Peterson has received personal compensation in the range of $0-$499 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Clinical Biochemistry. Dr. Peterson has received personal compensation in the range of $0-$499 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Lab Q for ASCP. Dr. Peterson has a non-compensated relationship as a President with Association of Medical Laboratory Immunologists that is relevant to AAN interests or activities.
Tom B. Martins, MS Mr. Martins has nothing to disclose.
Arevik Ghazaryan, PhD Dr. Ghazaryan has nothing to disclose.
Merina Toninelli Merina Toninelli has nothing to disclose.
Leo Lin, MD, PhD Dr. Lin has nothing to disclose.
Dorota Lebiedz-Odrobina, MD Dr. Lebiedz-Odrobina has nothing to disclose.
Tammy L. Smith, MD, PhD (Imaging and Neurosciences Center) Dr. Smith has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for EMD Serono. The institution of Dr. Smith has received research support from Alexion/AstraZeneca.