2021 Fall Conference | C19 - Anti-Amyloid Antibody Therapies in Alzheimer’s Disease: Considerations for Practice Implementation

Date Saturday 11/06/21

Time 03:00 PM - 07:00 PM EDT Add To Calendar

Session Format This program will be presented both in-person and online

On Demand This program will be available in the meeting's On Demand product.

Event Type Half-Day Course

Director(s) Vijay K. Ramanan, MD, PhD

Topic(s) Aging, Dementia, and Behavioral Neurology

Learning Objectives
Appraise major relevant findings from recent clinical trials of anti-amyloid therapies in Alzheimer's disease (AD)
Identify proposed clinical criteria and infrastructure/workflow components for appropriate use of anti-amyloid therapies in clinical practice
Understand imaging and fluid biomarkers relevant for anti-amyloid therapies in AD
Summarize features, mechanisms, risk factors, and safety approaches surrounding amyloid-related imaging abnormalities (ARIA)

CME Available 4.00 CME credits

Core Competencies Patient Care & Procedural Skills, Medical Knowledge, Systems-based Practice

Program Level Intermediate

Recommended Audience Fellow, Resident, General Neurologist, Specialist Neurologist, Advanced Practice Provider

Teaching Styles Didactic, Other

Program Materials Program Evaluations

Event Timeline
03:00 PM - 03:40 PM EDT	Introduction	Anti-Amyloid Therapies: Background, Mechanism, and Real-World Knowledge Gaps Vijay K. Ramanan, MD, PhD
03:40 PM - 04:30 PM EDT	Speaker	Appropriate Use Criteria for Aducanumab Liana Apostolova, MD, FAAN
04:30 PM - 05:10 PM EDT	Speaker	ARIA (Amyloid-Related Imaging Abnormalities) in Anti-Amyloid Therapies – Mechanism and Detection Petrice M. Cogswell, MD, PhD
05:10 PM - 05:20 PM EDT	Break
05:20 PM - 06:10 PM EDT	Speaker	Utilizing and Interpreting Amyloid Biomarkers for Anti-Amyloid Therapies – Neuroimaging and Fluid, Present and Future Gil D. Rabinovici, MD, FAAN
06:10 PM - 06:30 PM EDT	Speaker	Shared Decision-Making and Other Workflow Implications for Clinical Practice Vijay K. Ramanan, MD, PhD
06:30 PM - 07:00 PM EDT	Q&A	Live Q&A/Panel Discussion Vijay K. Ramanan, MD, PhD, Liana Apostolova, MD, FAAN, Gil D. Rabinovici, MD, FAAN, Petrice M. Cogswell, MD, PhD

Faculty Disclosures
Vijay K. Ramanan, MD, PhD	The institution of Dr. Ramanan has received research support from the National Institutes of Health. The institution of Dr. Ramanan has received research support from the Mangurian Foundation for Lewy Body Disease Research. The institution of Dr. Ramanan has received research support from as part of clinical trials sponsored by the Alzheimer's Association, Eisai, the Alzheimer's Treatment and Research Institute at USC, and Transposon Therapeutics, Inc.. The institution of Dr. Ramanan has received research support from Medscape. The institution of Dr. Ramanan has received research support from Expert Perspectives in Medicine. The institution of Dr. Ramanan has received research support from Roche/ADLM. The institution of Dr. Ramanan has received research support from American College of Radiology. Dr. Ramanan has received personal compensation in the range of $500-$4,999 for serving as a Conference Speaker/Organizer (Honoraria) with AANI. Dr. Ramanan has received personal compensation in the range of $500-$4,999 for serving as a Speaker/CME Content with Clinical Care Options.
Liana Apostolova, MD, FAAN	Dr. Apostolova has received personal compensation in the range of $500-$4,999 for serving as a Consultant for NIH. Dr. Apostolova has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Eli Lilly. Dr. Apostolova has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Roche. Dr. Apostolova has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for siemens. Dr. Apostolova has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Eisai. Dr. Apostolova has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Alnylam. Dr. Apostolova has received personal compensation in the range of $10,000-$49,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Alzheimer Association. The institution of Dr. Apostolova has received research support from Roche Diagnostics. The institution of Dr. Apostolova has received research support from NIA. The institution of Dr. Apostolova has received research support from Alzheimer Association. The institution of Dr. Apostolova has received research support from AVID radiopharmaceuticals. The institution of Dr. Apostolova has received research support from Life Molecular Imaging. Dr. Apostolova has a non-compensated relationship as a advisor with FDA that is relevant to AAN interests or activities.
Gil D. Rabinovici, MD, FAAN	Dr. Rabinovici has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Eli Lilly. Dr. Rabinovici has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Alector. Dr. Rabinovici has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Merck. Dr. Rabinovici has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Roche. Dr. Rabinovici has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Genentech. Dr. Rabinovici has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Novo Norodisk. Dr. Rabinovici has received personal compensation in the range of $500-$4,999 for serving as a Consultant for C2N. Dr. Rabinovici has received personal compensation in the range of $10,000-$49,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Johnson & Joihnson. Dr. Rabinovici has received personal compensation in the range of $10,000-$49,999 for serving on a Speakers Bureau for Peerview. Dr. Rabinovici has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Medscape. Dr. Rabinovici has received personal compensation in the range of $10,000-$49,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for JAMA Neurology. Dr. Rabinovici has received personal compensation in the range of $10,000-$49,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for JAMA. The institution of Dr. Rabinovici has received research support from NIH. The institution of Dr. Rabinovici has received research support from American College of Radiology. The institution of Dr. Rabinovici has received research support from Alzheimer's Association. The institution of Dr. Rabinovici has received research support from Rainwater Charitable Foundation. Dr. Rabinovici has received personal compensation in the range of $500-$4,999 for serving as a Topic Chair, Course Director and teacher with AAN. Dr. Rabinovici has received personal compensation in the range of $500-$4,999 for serving as a Grant reviewer with NIH. Dr. Rabinovici has received personal compensation in the range of $500-$4,999 for serving as a Invited speaker with ANA.
Petrice M. Cogswell, MD, PhD	Dr. Cogswell has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Eli Lilly. Dr. Cogswell has received personal compensation in the range of $5,000-$9,999 for serving as a Medical education speaker with Eisai. Dr. Cogswell has received personal compensation in the range of $500-$4,999 for serving as a Medical education speaker with Kaplan.

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