2026 Autoimmune Neurology Conference | C20 - CAR-T Cell Therapies and Neurology

Date Saturday 08/08/26

Time 02:45 PM - 04:30 PM CDT Add To Calendar

Location Marriott Marquis Houston | Texas G

Supported By This program is supported in part by an educational grant from Kyverna Therapeutics, Inc.

Session Format This program will be presented both in-person and online

On Demand This program will be available in the meeting's On Demand product.

Event Type Seminar

Moderator(s) Rachna Malani, MD, Monica E. Loghin, MD

Topic(s) Autoimmune Neurology

Learning Objectives Participants should be able to explain the fundamental principles and therapeutic uses of CAR-T cell therapies as they relate to neuroimmunology; identify common neurological complications associated with CAR-T cell treatment; and implement appropriate diagnostic and management strategies for patients experiencing CAR-T cell-related neurotoxicity.

CME Available 1.75 CME credits

Core Competencies Patient Care & Procedural Skills, Medical Knowledge, Practice-based Learning and Improvement

Program Level Advanced

Recommended Audience Fellow, Resident, General Neurologist, Specialist Neurologist, Non-neurologist, Advanced Practice Provider, Neurohospitalist, Medical Student

Teaching Styles Didactic

Program Materials Program Evaluations

Event Timeline
02:45 PM - 03:12 PM CDT	Speaker	CAR-T Cell Therapies: Basic Principles for the Neurologist Dimitrios Mougiakakos
03:12 PM - 03:39 PM CDT	Speaker	Neurological Complications of CAR-T Cell Therapies Bianca Santomasso, MD
03:39 PM - 04:06 PM CDT	Speaker	Neurological Indications for CAR-T Cell Therapies: Now and Into the Future Scott S. Zamvil, MD, PhD, FAAN
04:06 PM - 04:16 PM CDT	Abstract	1-015 - Clinical and Mechanistic Insights into Non-ICANS Neurotoxicity Following BCMA CAR T-cell Therapy Leonie Muller-Jensen, MD
04:16 PM - 04:26 PM CDT	Abstract	1-011 - Neurotoxicity from Bispecific T-cell Engagers: A Single Center Experience Donald Langan, Jr., MD

Faculty Disclosures
Rachna Malani, MD	Dr. Malani has nothing to disclose.
Monica E. Loghin, MD	Dr. Loghin has nothing to disclose.
Bianca Santomasso, MD	Dr. Santomasso has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Janssen/Johnson & Johnson. Dr. Santomasso has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Bristol-Myers Squibb. Dr. Santomasso has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Kite/Gilead. Dr. Santomasso has received personal compensation in the range of $500-$4,999 for serving as a Consultant for In8bio. Dr. Santomasso has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for In8bio. Dr. Santomasso has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Janssen Pharmaceuticals.
Scott S. Zamvil, MD, PhD, FAAN	Dr. Zamvil has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Sanofi-Genzyme. Dr. Zamvil has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Alexion. Dr. Zamvil has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Genzyme. Dr. Zamvil has received personal compensation in the range of $10,000-$49,999 for serving on a Speakers Bureau for Horizon. The institution of Dr. Zamvil has received personal compensation in the range of $10,000-$49,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for AAN. The institution of Dr. Zamvil has received research support from Sumaira Foundation. Dr. Zamvil has received personal compensation in the range of $5,000-$9,999 for serving as a Advisory Board with Genzyme. Dr. Zamvil has received personal compensation in the range of $500-$4,999 for serving as a Advisory Board with Genentech. Dr. Zamvil has received personal compensation in the range of $500-$4,999 for serving as a Advisory Board with Alexion.
Dimitrios Mougiakakos	Dimitrios Mougiakakos has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Kyverna Therapeutics. Dimitrios Mougiakakos has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Interius Bio. Dimitrios Mougiakakos has received personal compensation in the range of $500-$4,999 for serving as a Consultant for AvenCell. Dimitrios Mougiakakos has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Beigene. Dimitrios Mougiakakos has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Kite/Gilead. Dimitrios Mougiakakos has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for BMS. Dimitrios Mougiakakos has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Janssen. Dimitrios Mougiakakos has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Astra Zeneca. Dimitrios Mougiakakos has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Roche. Dimitrios Mougiakakos has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Abbvie.
Ari Green, MD	Dr. Green has received personal compensation in the range of $10,000-$49,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for JAMA Neurology. The institution of Dr. Green has received research support from Department of Defense. The institution of Dr. Green has received research support from Department of Defense. The institution of Dr. Green has received research support from NIH. The institution of Dr. Green has received research support from NIH / NINDS. The institution of Dr. Green has received research support from NIH / NINDS. Dr. Green has received intellectual property interests from a discovery or technology relating to health care.
Priya Dhawan, MD	Dr. Dhawan has nothing to disclose.
Sasha Gupta, MD	Dr. Gupta has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Legend . Dr. Gupta has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Genentech.
Ahmed Abdelhak, MD	The institution of Dr. Abdelhak has received research support from German Multiple Sclerosis Society.
Leonie Muller-Jensen, MD	The institution of Dr. Muller-Jensen has received research support from Else Kröner-Fresenius-Stiftung (EKFS). Dr. Muller-Jensen has received research support from Deutsche Forschungsgemeinschaft (DFG). Dr. Muller-Jensen has received personal compensation in the range of $0-$499 for serving as a Compensation for invited lecture with AAN.
Michelle A. Hughes, BS	Ms. Hughes has nothing to disclose.
Camille Fouassier	Mrs. Fouassier has nothing to disclose.
Jodi Lipof, MD	Dr. Lipof has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Kite/arcellx. Dr. Lipof has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Astrazeneca.
Taylor Hill	Miss Hill has nothing to disclose.
Omar Hernandez	Mr. Hernandez has nothing to disclose.
Bonell Patino-Escobar, MD	Dr. Patino-Escobar has nothing to disclose.
Arun Wiita, MD, PhD	Dr. Wiita has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Pfizer. Dr. Wiita has or had stock in Seen Therapeutics.
Shagun Arora, MD	Dr. arora has nothing to disclose.
Peter H. Sayre, MD, PhD	Dr. Sayre has nothing to disclose.
Serena S. Kwek, PhD	Dr. Kwek has nothing to disclose.
David Oh, MD, PhD	Dr. Oh has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Revelation Partners. Dr. Oh has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Tatum Biosciences. Dr. Oh has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Cartography Biosciences. The institution of Dr. Oh has received research support from Merck Sharp Dohme. The institution of Dr. Oh has received research support from PACT Pharma. The institution of Dr. Oh has received research support from Poseida Therapeutics. The institution of Dr. Oh has received research support from TCR2 Therapeutics. The institution of Dr. Oh has received research support from Roche/Genentech. The institution of Dr. Oh has received research support from Nutcracker Therapeutics. The institution of Dr. Oh has received research support from Amgen. The institution of Dr. Oh has received research support from Allogene. The institution of Dr. Oh has received research support from Clasp Therapeutics. The institution of Dr. Oh has received research support from Janux Therapeutics. Dr. Oh has received intellectual property interests from a discovery or technology relating to health care.
Jun Yan He	Mr. He has nothing to disclose.
Jeffrey L. Wolf, MD	Dr. Wolf has nothing to disclose.
Ajai Chari, MD	Dr. Chari has received personal compensation for serving as an employee of UCSF. Dr. Chari has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for abbvie. Dr. Chari has received personal compensation in the range of $500-$4,999 for serving as a Consultant for adaptive. Dr. Chari has received personal compensation in the range of $500-$4,999 for serving as a Consultant for amgen. Dr. Chari has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Antegene. Dr. Chari has received personal compensation in the range of $500-$4,999 for serving as a Consultant for BMS. Dr. Chari has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Forus. Dr. Chari has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Forus. Dr. Chari has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Genentech. Dr. Chari has received personal compensation in the range of $500-$4,999 for serving as a Consultant for GSK. Dr. Chari has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Janssen. Dr. Chari has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Karyopharm. Dr. Chari has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Takeda. Dr. Chari has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Sanofi. Dr. Chari has received research support from Janssen.
Thomas Martin, MD	Dr. Martin has received personal compensation for serving as an employee of GSK. Dr. Martin has received personal compensation for serving as an employee of Lilly. Dr. Martin has received personal compensation for serving as an employee of Pfizer. Dr. Martin has received personal compensation for serving as an employee of AstraZeneca. Dr. Martin has received personal compensation in the range of $500-$4,999 for serving as a Consultant for GSK. Dr. Martin has received personal compensation in the range of $500-$4,999 for serving as a Consultant for pfizer. Dr. Martin has received personal compensation in the range of $500-$4,999 for serving as a Consultant for astrazeneca. Dr. Martin has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for gsk. Dr. Martin has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for pfizer. Dr. Martin has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Eli Lilly and Company. Dr. Martin has received research support from sanofi. Dr. Martin has received research support from janssen. Dr. Martin has received research support from BMS.
Alfred Chung, MD	Dr. Chung has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Johnson and Johnson Innovative Medicine. Dr. Chung has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Bristol Myers-Squibb. The institution of Dr. Chung has received research support from Abbvie. The institution of Dr. Chung has received research support from Bristol Myers Squibb. The institution of Dr. Chung has received research support from Caelum Biosciences. The institution of Dr. Chung has received research support from CARsgen Therapeutics. The institution of Dr. Chung has received research support from Johnson and Johnson Innovative Medicine . The institution of Dr. Chung has received research support from K36 Therapeutics .
Darren Pan, MD	Dr. Pan has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Johnson and Johnson. Dr. Pan has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Pfizer. Dr. Pan has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Regeneron.
Anupama D. Kumar, MD	Dr. Kumar has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Astrazeneca. Dr. Kumar has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Legend. The institution of Dr. Kumar has received research support from Astrazeneca. The institution of Dr. Kumar has received research support from Bristol Myers Squibb. The institution of Dr. Kumar has received research support from Celgene.
Sarah F. Wesley, MD, MPH	Dr. Wesley has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Genentech. Dr. Wesley has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Novartis. Dr. Wesley has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for TG therapeutics. Dr. Wesley has a non-compensated relationship as a Trial Safety Monitor with Genentech that is relevant to AAN interests or activities.
Donald Langan, Jr., MD	Dr. Langan has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Genentech.
David Sabatino, PharmD	Dr. Sabatino has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Incyte.
Jiuling Yang	Jiuling Yang has nothing to disclose.
Lorena Perez-Amill	Lorena Perez-Amill has received personal compensation for serving as an employee of Gyala Therapeutics S.L. The institution of Lorena Perez-Amill has received research support from Spanish State Research Agency (AEI), Ministry of Science and Innovation, Spain. Lorena Perez-Amill has received intellectual property interests from a discovery or technology relating to health care. Lorena Perez-Amill has received intellectual property interests from a discovery or technology relating to health care.

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