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2026 Annual Meeting | S2 - Updates on Motor Neuron and Peripheral Nerve Disorders

Sunday 04/19/26
01:00 PM - 03:00 PM CDT Add To Calendar
McCormick Place West | W184d
This program will be presented both in-person and online
This program will be available in the meeting's On Demand product.
Scientific Platform Session
Senda Ajroud-Driss, MD, FAAN, Justin Y. Kwan, MD, FAAN
Neuromuscular and Clinical Neurophysiology (EMG)
2.00 CME credits

Program Materials

Event Timeline
01:00 PM - 01:24 PM CDT Speaker 2026 Sheila Essey Award: An Award for ALS Research: This award recognizes an individual who has made significant research contributions in the search for the cause, prevention of, and cure for amyotrophic lateral sclerosis (ALS)
Leonard Petrucelli, PhD
01:24 PM - 01:36 PM CDT Abstract 003 - Predictive Value of Cutaneous Biomarkers in Hereditary Transthyretin Amyloidosis
Sara Massucco, MD
01:36 PM - 01:48 PM CDT Abstract 004 - Enhancer Dysregulation in ALS: Evidence for Noncoding Regulatory Mechanisms in Neuronal Inflammation and Apoptosis
Guillermo K. Pons Monnier, MD
01:48 PM - 02:00 PM CDT Abstract 005 - Preliminary Findings on Serum Neurofilament Light Chain and Slow Vital Capacity in ALS Patients Treated With Edaravone: A Single-center Experience
Amaris Alayon, MD
02:00 PM - 02:12 PM CDT Abstract 006 - Sleep, Physical Activity and Incident Amyotrophic Lateral Sclerosis: A Large Prospective Cohort Study of Over 500,000 Participants
Jiali Xie
02:12 PM - 02:24 PM CDT Abstract 007 - CMT-HI Upper Limb Subscale Scores Respond to Treatment With Govorestat in Patients With CMT-SORD
Evan Bailey, MD
02:24 PM - 02:36 PM CDT Abstract 008 - Safety and Efficacy of Riliprubart, an Activated C1s-complement Inhibitor in CIDP: 76-week Phase Two Trial Results
Richard A. Lewis, MD, FAAN
02:36 PM - 02:48 PM CDT Abstract 009 - Clinical Characteristics and Treatment Response in Autoimmune Nodopathies: A Retrospective Review
Fabiola Valenzuela
02:48 PM - 03:00 PM CDT Abstract 010 - GHF-201, A Novel Oral Compound for Adult Polyglucosan Body Disease, Demonstrates Promising Safety and Efficacy in a Compassionate Use Program
Or Kakhlon, PhD
Faculty Disclosures
Senda Ajroud-Driss, MD, FAAN Dr. Ajroud-Driss has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Biogen. Dr. Ajroud-Driss has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Astrazeneca. Dr. Ajroud-Driss has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Biogen. The institution of Dr. Ajroud-Driss has received research support from NIH. The institution of Dr. Ajroud-Driss has received research support from University of Minesota/FDA. The institution of Dr. Ajroud-Driss has received research support from Edgewise Therapeutics. The institution of Dr. Ajroud-Driss has received research support from Biogen. The institution of Dr. Ajroud-Driss has received research support from Woolsey Pharmaceuticals. The institution of Dr. Ajroud-Driss has received research support from Uniqure Biopharma. The institution of Dr. Ajroud-Driss has received research support from Coya Therapeutics. The institution of Dr. Ajroud-Driss has received research support from Novartis. The institution of Dr. Ajroud-Driss has received research support from Alnylam pharmaceuticals. The institution of Dr. Ajroud-Driss has received research support from Healey and AMG center for ALS . The institution of Dr. Ajroud-Driss has received research support from les Turner ALS Foundation. The institution of Dr. Ajroud-Driss has received research support from Hopewell. The institution of Dr. Ajroud-Driss has received research support from Peripheral neuropathy foundation. Dr. Ajroud-Driss has received publishing royalties from a publication relating to health care.
Justin Y. Kwan, MD, FAAN Dr. Kwan has received research support from National Institutes of Health. Dr. Kwan has received personal compensation in the range of $100,000-$499,999 for serving as a Employee with National Institutes of Health.
Leonard Petrucelli, PhD Dr. Petrucelli has received personal compensation in the range of $10,000-$49,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Expansion Therapeutics. Dr. Petrucelli has received personal compensation in the range of $0-$499 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Science Translational Medicine. The institution of Dr. Petrucelli has received research support from Novoglia. The institution of Dr. Petrucelli has received research support from Biogen. Dr. Petrucelli has received intellectual property interests from a discovery or technology relating to health care. Dr. Petrucelli has received intellectual property interests from a discovery or technology relating to health care.
Lilian Maria Godeiro Coelho, MD Dr. Godeiro Coelho has nothing to disclose.
Richard A. Hughes, MD Dr. Hughes has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Sanofi.
Amaris Alayon, MD Ms. Alayon has nothing to disclose.
Christopher H. Gibbons, MD, FAAN Dr. Gibbons has received personal compensation for serving as an employee of CND Life Sciences. Dr. Gibbons has or had stock in CND Life Sciences.Dr. Gibbons has received publishing royalties from a publication relating to health care.
Alexander Lossos, MD Dr. Lossos has nothing to disclose.
Karla Cardenas-Soto, PhD Dr. Cardenas-Soto has nothing to disclose.
Eduardo Leon, MD Dr. Leon has nothing to disclose.
Caleb Dayley Mr. Dayley has received personal compensation for serving as an employee of Pentara Corporation.
Sara Massucco, MD Dr. Massucco has received research support from Italian Ministry of University and Research. Dr. Massucco has received research support from Beth Israel Deaconess Medical Center.
Jie Lin No disclosure on file
Yossi Gilgun-Sherki, PhD Dr. Gilgun-Sherki has nothing to disclose.
Nazem Atassi, MD Dr. Atassi has received personal compensation for serving as an employee of Sanofi. Dr. Atassi has stock in Sanofi.
Erik Wallstroem, MD, PhD Dr. Wallstroem has received personal compensation for serving as an employee of Sanofi. Dr. Wallstroem has stock in Sanofi. Dr. Wallstroem has received intellectual property interests from a discovery or technology relating to health care.
Chad R. Heatwole, MD, FAAN Dr. Heatwole has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Virginia Commonwealth University. Dr. Heatwole has received personal compensation in the range of $50,000-$99,999 for serving as a Consultant for Legal Med. Dr. Heatwole has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Neurocrine. Dr. Heatwole has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Novartis. Dr. Heatwole has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Swan Bio. Dr. Heatwole has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Harmony. Dr. Heatwole has received personal compensation in the range of $0-$499 for serving as a Consultant for Iris. Dr. Heatwole has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Recursion. Dr. Heatwole has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Avidity Biosciences. Dr. Heatwole has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Lupin. Dr. Heatwole has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Neurocrine. Dr. Heatwole has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Sanofi. Dr. Heatwole has received personal compensation in the range of $500-$4,999 for serving as an Expert Witness for New York Central Mutual. Dr. Heatwole has received personal compensation in the range of $500-$4,999 for serving as an Expert Witness for Penn Prop and Gas. The institution of Dr. Heatwole has received research support from Department of Defense. The institution of Dr. Heatwole has received research support from Novartis. The institution of Dr. Heatwole has received research support from MJFF. The institution of Dr. Heatwole has received research support from FARA. The institution of Dr. Heatwole has received research support from NIH. The institution of Dr. Heatwole has received research support from University of Miami. The institution of Dr. Heatwole has received research support from MDA. Dr. Heatwole has received intellectual property interests from a discovery or technology relating to health care.
Kristen Auwarter, MD Dr. Auwarter has received personal compensation for serving as an employee of Sanofi. An immediate family member of Dr. Auwarter has received personal compensation for serving as an employee of Medtronic. Dr. Auwarter has stock in Sanofi.
Evan Bailey, MD Mr. Bailey has received personal compensation for serving as an employee of Applied Therapeutics, Inc. Mr. Bailey has stock in Applied Therapeutics, Inc.
Miguel Alonso Alonso Miguel Alonso Alonso has received personal compensation for serving as an employee of Sanofi. Miguel Alonso Alonso has stock in Sanofi.
Fabiola Valenzuela Dr. Valenzuela has nothing to disclose.
Qiang Lu, MD Dr. Lu has nothing to disclose.
Samuel Dickson Mr. Dickson has nothing to disclose.
Miguel Weil, PhD Prof. Weil has nothing to disclose.
Miranda de la Pena-Tamez Miss de la Pena-Tamez has nothing to disclose.
Jennifer Luth Jennifer Luth has received personal compensation for serving as an employee of Applied Therapeutics.
Hector R. Martinez, MD Dr. Martinez has nothing to disclose.
Catherine Summers No disclosure on file
Nissim Garti, Sr., PhD Prof. Garti has nothing to disclose.
Hans-Peter Hartung, MD, FAAN Dr. Hartung has received personal compensation in the range of $500-$4,999 for serving as a Consultant for BMS Celgene. Dr. Hartung has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Geneuro. Dr. Hartung has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Novartis. Dr. Hartung has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Novartis. Dr. Hartung has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Merck. Dr. Hartung has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Bayer. Dr. Hartung has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for TG Therapeutics. Dr. Hartung has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Roche. Dr. Hartung has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Frontiers Neurology.
Emmanuel Martinez-Ledesma, PhD Dr. Martinez-Ledesma has nothing to disclose.
Mary Vo, MD Dr. Vo has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Alexion. Dr. Vo has received personal compensation in the range of $10,000-$49,999 for serving as an Expert Witness for Phillips and Paolicchi.
Shahram Attarian, MD, PhD Prof. Attarian has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for SANOFI, Pfizer LFB, Alnylam Biogen Argenx, UCB Alexion, Astrazenica, Amicus, Janssen, Novartis, Roche. Prof. Attarian has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for SANOFI, Biogen,Alnylam, Argenx, USB, Alexion Astrazenica, Janssen, Roche, Amgen. The institution of Prof. Attarian has received research support from National Institut of Health .
Guillermo K. Pons Monnier, MD Dr. Pons Monnier has nothing to disclose.
Hong-Fu Li, MD, PhD Dr. Li has nothing to disclose.
Maria Alejandra Gonzalez Duarte, MD, FAAN Dr. Gonzalez Duarte has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Alnylam. Dr. Gonzalez Duarte has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Astra Zeneca. Dr. Gonzalez Duarte has received personal compensation in the range of $10,000-$49,999 for serving on a Speakers Bureau for Alnylam . The institution of Dr. Gonzalez Duarte has received research support from Pfizer.
Juan P. Cabrera Pulla, MD Dr. Cabrera Pulla has nothing to disclose.
Annie Dionne, MD Dr. Dionne has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Sanofi. Dr. Dionne has received research support from Sanofi.
Jaya Trivedi, MD, FAAN The institution of Dr. Trivedi has received research support from Avidity.
Anat Mordechai, RN Mrs. MORDECHAI has nothing to disclose.
Nerea Martin Del Campo Guinovart Miss Martin Del Campo Guinovart has nothing to disclose.
Mark T. Roberts, MD Dr. Roberts has nothing to disclose.
Paige L. Harmon, MD Dr. Harmon has nothing to disclose.
Richard A. Lewis, MD, FAAN Dr. Lewis has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Argenx. Dr. Lewis has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for CSL Behring. Dr. Lewis has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Sanofi. Dr. Lewis has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Grifols. Dr. Lewis has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Takeda. Dr. Lewis has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Nuvig. Dr. Lewis has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Dianthus. Dr. Lewis has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Janssen. Dr. Lewis has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Medscape. Dr. Lewis has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Annexon. Dr. Lewis has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Immunovant. Dr. Lewis has received personal compensation in the range of $500-$4,999 for serving as a Consultant for BioCryst. Dr. Lewis has received personal compensation in the range of $500-$4,999 for serving as a Consultant for NervoSave. Dr. Lewis has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Annexon. Dr. Lewis has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Alexion. Dr. Lewis has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Amgen. Dr. Lewis has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Immunovant. Dr. Lewis has received personal compensation in the range of $500-$4,999 for serving as a Consultant for TGTX. Dr. Lewis has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Boehringer-Ingleheim. Dr. Lewis has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Intellia. Dr. Lewis has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Cartesian. Dr. Lewis has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for CME Outfitters. Dr. Lewis has received personal compensation in the range of $500-$4,999 for serving as a Consultant for PeerVision. Dr. Lewis has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Up to Date. Dr. Lewis has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Alexion. Dr. Lewis has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Boehringer Ingelheim. Dr. Lewis has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Alnylam. Dr. Lewis has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Novartis. Dr. Lewis has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Intellia. Dr. Lewis has received personal compensation in the range of $5,000-$9,999 for serving as an Expert Witness for Shernoff et al. Dr. Lewis has received publishing royalties from a publication relating to health care.
Luis Querol, MD, PhD Dr. Querol has received personal compensation in the range of $500-$4,999 for serving as a Consultant for CSL Behring. The institution of Dr. Querol has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for UCB. Dr. Querol has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for ArgenX. Dr. Querol has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Takeda. Dr. Querol has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Dianthus. Dr. Querol has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Alnylam. Dr. Querol has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Annexon. Dr. Querol has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Avilar. Dr. Querol has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Biocryst. Dr. Querol has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Immunovant. Dr. Querol has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Lundbeck. Dr. Querol has received personal compensation in the range of $500-$4,999 for serving as a Consultant for KPL. Dr. Querol has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Lycia. The institution of Dr. Querol has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Sanofi. Dr. Querol has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Sanofi. Dr. Querol has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Novartis. Dr. Querol has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Roche. The institution of Dr. Querol has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Sanofi. Dr. Querol has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for ArgenX. Dr. Querol has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Roche. Dr. Querol has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Merck. Dr. Querol has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Grifols. The institution of Dr. Querol has received research support from GBS-CIDP Foundation International. The institution of Dr. Querol has received research support from Grifols. The institution of Dr. Querol has received research support from ISCIII. The institution of Dr. Querol has received research support from CIBERER. The institution of Dr. Querol has received research support from UCB. The institution of Dr. Querol has received research support from ArgenX.
Michael E. Shy, MD, FAAN Dr. Shy has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Applied Therapeutics. The institution of Dr. Shy has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for DTx Pharma. The institution of Dr. Shy has received research support from NIH. The institution of Dr. Shy has received research support from Muscular Dystrophy Association. The institution of Dr. Shy has received research support from Charcot Marie Tooth Association. The institution of Dr. Shy has received research support from Applied Therapeutics.
Pieter Van Doorn, MD The institution of Dr. Van Doorn has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Argenx. The institution of Dr. Van Doorn has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Hansa. The institution of Dr. Van Doorn has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Sanofi. The institution of Dr. Van Doorn has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Octapharma. The institution of Dr. Van Doorn has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Annexon. The institution of Dr. Van Doorn has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Grifols. The institution of Dr. Van Doorn has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Octapharma. The institution of Dr. Van Doorn has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Argenx. Dr. Van Doorn has received publishing royalties from a publication relating to health care.
Raquel Cuevas-Diaz Duran, PhD Dr. Cuevas-Diaz Duran has nothing to disclose.
Oscar E. Gutierrez Trevino, MD Dr. Gutierrez Trevino has nothing to disclose.
Jiali Xie Jiali Xie has nothing to disclose.
Or Kakhlon, PhD Or Kakhlon, PhD has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Golden Heart Flower. Or Kakhlon, PhD has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Golden Heart Flower.
Roy L. Freeman, MD Dr. Freeman has received personal compensation in the range of $50,000-$99,999 for serving as a Consultant for Cutaneous Diagnostic Life Sciences. Dr. Freeman has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Vertex. Dr. Freeman has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Theravance. Dr. Freeman has received personal compensation in the range of $10,000-$49,999 for serving as an officer or member of the Board of Directors for Inhibikase. Dr. Freeman has received personal compensation in the range of $10,000-$49,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Elsevier. The institution of Dr. Freeman has received research support from NIH. The institution of Dr. Freeman has received research support from Theravance. The institution of Dr. Freeman has received research support from Biohaven. The institution of Dr. Freeman has received research support from Lundbeck. Dr. Freeman has received research support from Regeneron.
Olimpia Carbunar, MD The institution of Dr. Carbunar has received research support from National Institute of Arthritis and Musculoskeletal and Skin Diseases. The institution of Dr. Carbunar has received research support from ARGENX/PPD.