2026 Annual Meeting | S21 - Neurocritical Care

Date Tuesday 04/21/26

Time 01:00 PM - 03:00 PM CDT Add To Calendar

Location McCormick Place West | W193a

Session Format This program will be presented both in-person and online

On Demand This program will be available in the meeting's On Demand product.

Event Type Scientific Platform Session

Moderator(s) Minjee Kim, MD, Marc Alain Babi, MD

Topic(s) Neurocritical Care, Neuro Trauma and Critical Care

CME Available 2.00 CME credits

Program Materials

Event Timeline
01:00 PM - 01:12 PM CDT	Abstract	001 - Safety and Tolerability of GTX-104 (Nimodipine Injection for IV Infusion) Compared With Oral Nimodipine in Patients With Aneurysmal Subarachnoid Hemorrhage: A Prospective, Randomized Trial Loch Macdonald, MD, PhD
01:12 PM - 01:24 PM CDT	Abstract	002 - Early Targeted C1q Inhibition With Tanruprubart Improves Functional Recovery in Guillain-Barré Syndrome: Results From a Phase Three Study Henk-Andre A. Kroon, MD, MBA
01:24 PM - 01:36 PM CDT	Abstract	003 - Machine Learning Models to Predict Withdrawal of Life-sustaining Therapy in Patients With Severe Traumatic Brain Injury Michael D. Cobler-Lichter, MD
01:36 PM - 01:48 PM CDT	Abstract	004 - Sex-specific Proteomic Signatures of the SUR1-TRPM4 Pathway in Plasma and Cerebrospinal Fluid after Severe Traumatic Brain Injury Anupama Rani, PhD
01:48 PM - 02:00 PM CDT	Abstract	005 - Development and External Validation of Machine Learning Models for Sepsis Prediction in Aneurysmal Subarachnoid Hemorrhage Dhruv Patel, MD
02:00 PM - 02:12 PM CDT	Abstract	006 - Comprehensive Plasma Biomarker Profiling Identifies Inflammatory and Glial Pathways Linked to Severity in Status Epilepticus Karnig Kazazian, PhD
02:12 PM - 02:24 PM CDT	Abstract	007 - A Specialized Neuroprognostication Program is Associated With Improved Guideline-adherence and Outcomes after Cardiac Arrest David J. Fischer, MD
02:24 PM - 02:36 PM CDT	Abstract	008 - Middle Meningeal Artery Embolization Compared With Conventional Management in Chronic Subdural Hematoma: An Umbrella Review of Meta-analyses Wesley Julius, MD
02:36 PM - 02:48 PM CDT	Abstract	009 - Single-cell Transcriptomics Reveals Inflammatory Remodeling of the Choroid Plexus after Traumatic Brain Injury Milo Taylor
02:48 PM - 03:00 PM CDT	Abstract	010 - Spreading Depolarization Burden Association With Neurological Recovery Following Traumatic Brain Injury Adeline Hayman

Faculty Disclosures
Minjee Kim, MD	The institution of Dr. Kim has received research support from Genentech, Inc.. The institution of Dr. Kim has received research support from National Institute on Aging.
David J. Fischer, MD	Dr. Fischer has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Alphasights. Dr. Fischer has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Atheneum. Dr. Fischer has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Becton Dickinson. Dr. Fischer has received personal compensation in the range of $5,000-$9,999 for serving as an Expert Witness for Drazin & Warshaw. The institution of Dr. Fischer has received research support from NIH/NINDS. The institution of Dr. Fischer has received research support from ��ɫ��. The institution of Dr. Fischer has received research support from Neurocritical Care Society.
Andrea L. Schneider, MD, PhD	Dr. Schneider has received personal compensation in the range of $10,000-$49,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for AAN - Neurology.
Karnig Kazazian, PhD	Dr. Kazazian has nothing to disclose.
Dhivyaa Rajasundaram	Dhivyaa Rajasundaram has nothing to disclose.
Roxanne L. Simmons, MD	Dr. Simmons has nothing to disclose.
Felipe C. Albuquerque, MD	Dr. Albuquerque has nothing to disclose.
Kaspar Keledjian, MD	Dr. Keledjian has nothing to disclose.
Semeon Afework	Mr. Afework has nothing to disclose.
Xiaoyu Zhou, MA	Mrs. Zhou has nothing to disclose.
Michael D. Cobler-Lichter, MD	Dr. Cobler-Lichter has nothing to disclose.
Michael Huang, MD	Dr. Huang has nothing to disclose.
Hannah G. Gray, MSc	Ms. Gray has received personal compensation in the range of $500-$4,999 for serving as a AAN 2025 Annual Meeting Abstract Co-Author and Presenter with Creyos.
Erik Pulkstenis, PhD	Dr. Pulkstenis has received personal compensation for serving as an employee of Annexon Biosciences. Dr. Pulkstenis has stock in Annexon Biosciences. Dr. Pulkstenis has stock in AbbVie.
Dua Gul, MBBS	Dr. Gul has nothing to disclose.
Prajwal Ciryam, MD, PhD	The institution of Dr. Ciryam has received research support from Henry M. Jackson Foundation. The institution of Dr. Ciryam has received research support from Passano Foundation. The institution of Dr. Ciryam has received research support from GEn1E Lifesciences. The institution of Dr. Ciryam has received research support from Brain Aneurysm Foundation. The institution of Dr. Ciryam has received research support from Neurocritical Care Foundation. The institution of Dr. Ciryam has received research support from Center for Shock, Trauma, and Anesthesiology Research, University of Maryland.
Teneille Gofton, MD	The institution of Dr. Gofton has received research support from Government of Canada. The institution of Dr. Gofton has received research support from Canadian Institutes of Health Research. The institution of Dr. Gofton has received research support from Academic Medical Organisation of Southwestern Ontario. The institution of Dr. Gofton has received research support from Lawson Health Research Institute. Dr. Gofton has a non-compensated relationship as a Medical Advisory Board Member with NORSE Institute that is relevant to AAN interests or activities.
Danelle Czink	Ms. Czink has nothing to disclose.
Maharshi Pandya	Mr. Pandya has nothing to disclose.
Sirin Gandhi, MD	Dr. Gandhi has nothing to disclose.
Amedeo Merenda, MD	Dr. Merenda has nothing to disclose.
Patrick M. Kochanek, MD, MCCM	Patrick M. Kochanek, MD, MCCM has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for University of Washington. Patrick M. Kochanek, MD, MCCM has received personal compensation in the range of $10,000-$49,999 for serving as an Expert Witness for Johns Hopkins Health System. Patrick M. Kochanek, MD, MCCM has received personal compensation in the range of $10,000-$49,999 for serving as an Expert Witness for de Boisblanc Law Firm. The institution of Patrick M. Kochanek, MD, MCCM has received research support from Chuck Noll Foundation. The institution of Patrick M. Kochanek, MD, MCCM has received research support from NIH. Patrick M. Kochanek, MD, MCCM has received publishing royalties from a publication relating to health care.
Huimahn A. Choi, MD	The institution of Dr. Choi has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Acasti Pharma.
Ethan Gaskin, MS	Mr. Gaskin has nothing to disclose.
Jane Hwang	Ms. Hwang has nothing to disclose.
Jose C. Navarro, MD	Dr. Navarro has nothing to disclose.
Kristine H. O'Phelan, MD	Dr. O'Phelan has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Bard Medical. Dr. O'Phelan has a non-compensated relationship as a DSMB member SIREN network with NIH/NINDS that is relevant to AAN interests or activities.
Britta Lindquist, MD, PhD	The institution of Dr. Lindquist has received research support from National Institutes of Health NINDS.
Vikash Kumar Karmani, MBBS	Dr. Karmani has nothing to disclose.
JOACIR G. Cordeiro, MD, PhD	Dr. Cordeiro has nothing to disclose.
Sherry Hsiang-Yi Chou, MD	Dr. Hsiang-Yi Chou has received personal compensation for serving as an employee of NIH. An immediate family member of Dr. Hsiang-Yi Chou has received personal compensation for serving as an employee of Wells Fargo. Dr. Hsiang-Yi Chou has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Grace Therapeutics. The institution of Dr. Hsiang-Yi Chou has received research support from The Neurocritical Care Society. Dr. Hsiang-Yi Chou has a non-compensated relationship as a Board of Director member with United Council of Neurologic Specialties that is relevant to AAN interests or activities. Dr. Hsiang-Yi Chou has a non-compensated relationship as a Co-chair/chair-elect, the Neurocritical Care Committee with American Heart Association, the Stroke Council that is relevant to AAN interests or activities. Dr. Hsiang-Yi Chou has a non-compensated relationship as a Co-chair/chair ellect, the Neurocritical Care Special Interest Group with American Neurologic Association that is relevant to AAN interests or activities.
Jessica Delamater, MD	Dr. Delamater has nothing to disclose.
Ana Reyes, MD	Dr. Reyes has nothing to disclose.
Raemier Javelosa	Ms. Javelosa has nothing to disclose.
Saleem M. Halablab, MD	Dr. Halablab has nothing to disclose.
Kevin Bao	Mr. Bao has nothing to disclose.
Matheus Otero, MD	Dr. Otero has nothing to disclose.
Khan Abul Kalam Azad, MD, MBBS, MACP, FRCP	Prof. Azad has nothing to disclose.
Nina M. Massad, MD	Dr. Massad has nothing to disclose.
Quazi Deen Mohammad, MD	Dr. Deen Mohammad has nothing to disclose.
Talia Arcieri	Ms. Arcieri has nothing to disclose.
Dhruv Patel, MD	Dr. Patel has nothing to disclose.
Andrew Ducruet, MD	Andrew Ducruet, MD has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Kos. Andrew Ducruet, MD has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Medtronic. Andrew Ducruet, MD has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Phenox. Andrew Ducruet, MD has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Penumbra. Andrew Ducruet, MD has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Grace Therapeutics. The institution of Andrew Ducruet, MD has received research support from National Institute of Health.
Connor A. Law, BS	Mr. Law has nothing to disclose.
Loch Macdonald, MD, PhD	Dr. Macdonald has received personal compensation for serving as an employee of Grace Therapeutics. Dr. Macdonald has received personal compensation in the range of $50,000-$99,999 for serving as a Consultant for Grace Therapeutics. Dr. Macdonald has stock in Grace Therapeutics. The institution of Dr. Macdonald has received research support from Community Health Partners. Dr. Macdonald has received publishing royalties from a publication relating to health care. Dr. Macdonald has received personal compensation in the range of $500-$4,999 for serving as a Grant reviewer with National Institutes of Health.
David J. Caldwell, MD, PhD	The institution of Dr. Caldwell has received research support from NIH.
Michael T. Lawton, MD	The institution of Dr. Lawton has received personal compensation in the range of $50,000-$99,999 for serving as a Consultant for Zeiss. Dr. Lawton has received intellectual property interests from a discovery or technology relating to health care. Dr. Lawton has received personal compensation in the range of $500-$4,999 for serving as a Visiting Professor with Visiting Professor Honorariums.
Margaux Miller	Ms. Miller has nothing to disclose.
Orest Tsymbalyuk	Orest Tsymbalyuk has nothing to disclose.
Joshua Catapano, MD	Dr. Catapano has nothing to disclose.
Wesley Julius, MD	Dr. Julius has nothing to disclose.
Vladimir Gerzanich, MD, PhD	The institution of Dr. Gerzanich has received research support from NIH.
Aurelia Cors	An immediate family member of Ms. Cors has received personal compensation in the range of $100,000-$499,999 for serving as a Office Director with US Environmental Protection Agency. An immediate family member of Ms. Cors has received personal compensation in the range of $100,000-$499,999 for serving as a Attorney with US Department of Justice.
Katherine Peterson	Ms. Peterson has nothing to disclose.
Kavi Patel	Mr. Patel has nothing to disclose.
Mohan Kottapally, MD	Dr. Kottapally has nothing to disclose.
Jonathan Jagid	Jonathan Jagid has received personal compensation in the range of $10,000-$49,999 for serving as an Expert Witness for Miami Dade County State Attorneys office. The institution of Jonathan Jagid has received research support from Boston Scientific.
John K. Yue, MD	The institution of Dr. Yue has received research support from University of California San Francisco Weill Neurohub. The institution of Dr. Yue has received research support from University of California San Francisco Weill Institute for the Neurosciences and University of California San Francisco Innovation Ventures Catalyst Award Grant.
Aleksandra Leligdowicz, MD, PhD	The institution of Dr. Leligdowicz has received research support from Academic Medical Organization of Southwestern Ontario. Dr. Leligdowicz has received personal compensation in the range of $0-$499 for serving as a Associate Editor with Critical Care.
Anupama Rani, PhD	Dr. Rani has nothing to disclose.
W. T. Kimberly, MD, PhD	Dr. Kimberly has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Astrocyte Pharmaceuticals. Dr. Kimberly has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Acasti Pharma. Dr. Kimberly has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Takeda. Dr. Kimberly has received personal compensation in the range of $0-$499 for serving on a Scientific Advisory or Data Safety Monitoring board for Stryker. Dr. Kimberly has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Neurotherapeutics. Dr. Kimberly has stock in Woolsey Pharmaceuticals. Dr. Kimberly has stock in Acasti Pharma. The institution of Dr. Kimberly has received research support from NIH. The institution of Dr. Kimberly has received research support from Hyperfine, Inc.. The institution of Dr. Kimberly has received research support from Alzheimer's Association. Dr. Kimberly has received intellectual property interests from a discovery or technology relating to health care.
Geoffrey Manley, MD, PhD	The institution of Dr. Manley has received research support from NIH-NINDS. The institution of Dr. Manley has received research support from US Department of Defense. The institution of Dr. Manley has received research support from US Department of Defense/MTEC. The institution of Dr. Manley has received research support from One Mind. The institution of Dr. Manley has received research support from Neurotrauma Sciences, LLC. The institution of Dr. Manley has received research support from NFL Scientific Advisory Board.
Kaitlyn Hebig	Ms. Hebig has nothing to disclose.
Brian Manolovitz, PhD	Dr. Manolovitz has nothing to disclose.
Adam Eberle	Mr. Eberle has nothing to disclose.
J Marc Simard, MD, PhD	Dr. Simard has nothing to disclose.
Adeline Hayman	Ms. Hayman has nothing to disclose.
Ayham M. Alkhachroum, MD	The institution of Dr. Alkhachroum has received research support from Miami CTSI.
Ruchira M. Jha, MD	Dr. Jha has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Biogen. An immediate family member of Dr. Jha has received personal compensation in the range of $5,000-$9,999 for serving as an Expert Witness for Legal fees. The institution of Dr. Jha has received research support from NIH/NINDS, Chuck Noll Foundation, University of Pittsburgh, Barrow Neurological Foundation.
Vishnu Karukonda	Mr. Karukonda has nothing to disclose.
Nicholas Namias, MD	Dr. Namias has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Molnycke.
Tulay Koru-Sengul, PhD	Dr. Koru-Sengul has nothing to disclose.
Alejandro A. Rabinstein, MD, FAAN	Dr. Rabinstein has received personal compensation in the range of $10,000-$49,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Boston Scientific. Dr. Rabinstein has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Shionogi . Dr. Rabinstein has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Chiesi. Dr. Rabinstein has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Ceribell. Dr. Rabinstein has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Neurocritical care/NCS-Springer. Dr. Rabinstein has received personal compensation in the range of $5,000-$9,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Wolters/UptoDate. Dr. Rabinstein has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for EBSCO/DynaMed. Dr. Rabinstein has received personal compensation in the range of $5,000-$9,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for AHA. Dr. Rabinstein has received publishing royalties from a publication relating to health care. Dr. Rabinstein has received publishing royalties from a publication relating to health care. Dr. Rabinstein has received publishing royalties from a publication relating to health care. Dr. Rabinstein has received publishing royalties from a publication relating to health care.
Glenn Morrison, PhD	Dr. Morrison has received personal compensation for serving as an employee of Alector. Dr. Morrison has received personal compensation in the range of $500-$4,999 for serving as a Consultant for GLG . Dr. Morrison has stock in Alector. Dr. Morrison has received intellectual property interests from a discovery or technology relating to health care.
NASATHAPOT NAMPHOL, MD	Dr. NAMPHOL has nothing to disclose.
Thomas Donovan, MSc	Mr. Donovan has nothing to disclose.
Milo Taylor	Mr. Taylor has received research support from National Institutes of Health.
Edilberto Amorim, MD	The institution of Dr. Amorim has received research support from American Heart Association. The institution of Dr. Amorim has received research support from Society of Critical Care Medicine. The institution of Dr. Amorim has received research support from Zoll Foundation. The institution of Dr. Amorim has received research support from Hellman Foundation. The institution of Dr. Amorim has received research support from Regents of the University of California. The institution of Dr. Amorim has received research support from Citizens United Against Epilepsy. The institution of Dr. Amorim has received research support from Regents of the University of California. The institution of Dr. Amorim has received research support from American Heart Association. The institution of Dr. Amorim has received research support from NIH. The institution of Dr. Amorim has received research support from Department of Defense. The institution of Dr. Amorim has received research support from Department of Defense. The institution of Dr. Amorim has received research support from American Heart Association.
Shreya Satheesh, Student	Ms. Satheesh has nothing to disclose.
Ashutosh P. Jadhav, MD, FAAN	Dr. Jadhav has nothing to disclose.
Sabrina A. Mann	Ms. Mann has nothing to disclose.
John McKeown, PhD	Dr. McKeown has received personal compensation for serving as an employee of University of Miami Miller School of Medicine.
Claude Hemphill III, MD, FAAN	Dr. Hemphill has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Zoll. Dr. Hemphill has received personal compensation in the range of $0-$499 for serving on a Scientific Advisory or Data Safety Monitoring board for Aurenar. Dr. Hemphill has received personal compensation in the range of $10,000-$49,999 for serving as an Expert Witness for various legal firms. The institution of Dr. Hemphill has received research support from NIH/NINDS.
Victoria Labuda, BMSc	Ms. Labuda has nothing to disclose.
Erin McNally, BS	Miss McNally has nothing to disclose.
Anthony Mefford, MD	Dr. Mefford has nothing to disclose.
Diana L. Monge Sanchez, MD	Dr. Monge Sanchez has received research support from Barrow Neurological Foundation.
Aditya Kumar, MD	Dr. Kumar has nothing to disclose.
Laura Snyder, MD	Dr. Snyder has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Medtronic. Dr. Snyder has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Globus.
Fernanda Jacinto Pereira Teixeira, MD	Dr. Jacinto Pereira Teixeira has nothing to disclose.
Zhahirul Islam	Zhahirul Islam has nothing to disclose.
Henk-Andre A. Kroon, MD, MBA	Dr. Kroon has received personal compensation for serving as an employee of Annexon Biosciences. Dr. Kroon has stock in Annexon Biosciences.
Lawrence Chyall, RN, MS, CNS	Mr. Chyall has nothing to disclose.
Marc Alain Babi, MD	Dr. Babi has nothing to disclose.

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