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2026 Annual Meeting | S42 - Perspectives on Non-Alzheimer's Dementia Diagnostics and Therapeutics

Wednesday 04/22/26
01:00 PM - 03:00 PM CDT Add To Calendar
McCormick Place West | W196b
This program will be presented both in-person and online
This program will be available in the meeting's On Demand product.
Scientific Platform Session
Lealani M. Acosta, MD, MPH, FAAN, Sandeepa Mullady, MD
Aging, Dementia, and Behavioral Neurology
2.00 CME credits

Program Materials

Event Timeline
01:00 PM - 01:12 PM CDT Abstract 001 - Longitudinal Changes in Brain Diffusion Characteristics Associated with Cognition and Vascular Risk Factors: The ARIC-NCS Study
Yuto Uchida, MD, PhD
01:12 PM - 01:24 PM CDT Abstract 002 - Dorsal and Ventral Pathways for Words and Sentences Processing
Marco Catani, MD, PhD
01:24 PM - 01:36 PM CDT Abstract 003 - Premature Brain Aging and Choroid Plexus Enlargement in Young Adults with Psychosis
Neslihan Yildiz Ozhan, MD
01:36 PM - 01:48 PM CDT Abstract 004 - Digital Speech Markers of Lexical Dysfluency in Primary Progressive Aphasia
Jet M. Vonk, PhD, PhD
01:48 PM - 02:00 PM CDT Abstract 005 - The Use of a Rapid Biosensor Assay Identifies Co-pathology and Atypical Patterns in Tauopathies
Nil Saez Calveras, MD
02:00 PM - 02:12 PM CDT Abstract 006 - Accelerated High-dose rTMS for Post-stroke Apathy: A Pilot Trial
Parneet K. Grewal, MD
02:12 PM - 02:24 PM CDT Abstract 007 - Convergent Causal Mapping of Memory and a Brain Stimulation Target for Memory Dysfunction
Calvin W. Howard, MD
02:24 PM - 02:36 PM CDT Abstract 008 - Age-related Neurodegenerative Diseases Represent Common Causes of Rapidly Progressive Dementia: A Clinicopathological Study
Evelyn Lazar, MD
02:36 PM - 02:48 PM CDT Abstract 009 - Vesicular and Immune Dysregulation Identified Through Transcriptomic and Proteomic Profiling in Mixed Dementia with Alzheimer’s and Lewy Body Pathologies
Gurkan Bebek, PhD
02:48 PM - 03:00 PM CDT Abstract 010 - The Syn-D Study: Detection of Longitudinal Changes in Cutaneous Phosphorylated Alpha-Synuclein in Mild Cognitive Impairment
Roy L. Freeman, MD
Faculty Disclosures
Lealani M. Acosta, MD, MPH, FAAN Dr. Acosta has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Alector. Dr. Acosta has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Neurology. The institution of Dr. Acosta has received research support from AbbVie, Sage, NIH, Bristol Myers Squibb/Fortrea, CND Life Sciences.
Sandeepa Mullady, MD Dr. Mullady has nothing to disclose.
Jessica Deleon, MD The institution of Dr. Deleon has received research support from NIH.
Ryan Colyer No disclosure on file
Yasin Temel No disclosure on file
Christopher H. Gibbons, MD, FAAN Dr. Gibbons has received personal compensation for serving as an employee of CND Life Sciences. Dr. Gibbons has or had stock in CND Life Sciences.Dr. Gibbons has received publishing royalties from a publication relating to health care.
Maurizio Corbetta, MD Dr. Corbetta has nothing to disclose.
Andres M. Lozano, MD Dr. Lozano has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Abbott. Dr. Lozano has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Insightec. Dr. Lozano has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Boston Scientific. Dr. Lozano has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Medtronic. Dr. Lozano has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Functional Neuromodulation.
Jens Kuhn No disclosure on file
Andreas Horn, MD, PhD Dr. Horn has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Boston Scientific.
Savir Madan Mr. Madan has nothing to disclose.
Michael Coleman Mr. Coleman has nothing to disclose.
Matcheri S. Keshavan, MD Dr. Keshavan has nothing to disclose.
Suheyla Cetin-Karayumak, PhD Dr. Cetin-Karayumak has nothing to disclose.
Bhim Adhikari, PhD Dr. Adhikari has nothing to disclose.
Jet M. Vonk, PhD, PhD Dr. Vonk has nothing to disclose.
Nicole Tamvaka, BSc Ms. Tamvaka has nothing to disclose.
Rohit Bakshi, MD, FAAN Dr. Bakshi has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for EMD Serono. Dr. Bakshi has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Sanofi. The institution of Dr. Bakshi has received personal compensation in the range of $10,000-$49,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Journal of Neuroimaging. The institution of Dr. Bakshi has received research support from Bristol Myers Squibb. The institution of Dr. Bakshi has received research support from EMD Serono. The institution of Dr. Bakshi has received research support from Novartis.
Zoe Ezzes Ms. Ezzes has received research support from NIH (T32 training grant).
Pablo Andrade, MD Dr. Andrade has nothing to disclose.
Alissa Nana Li, PhD The institution of Dr. Nana Li has received research support from NIH.
Michael D. Fox, MD, PhD Dr. Fox has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Wiley.
Morganne Smith The institution of Mrs. Smith has received research support from Sorridi Therapeutics.
Brittany T. Morin Mrs. Morin has nothing to disclose.
Mae Morton-Dutton Mae Morton-Dutton has nothing to disclose.
Marc Diamond, MD The institution of Dr. Diamond has received research support from NIH. Dr. Diamond has received intellectual property interests from a discovery or technology relating to health care.
Gopala K. Anumanchipalli, PhD Prof. Anumanchipalli has nothing to disclose.
Shan Siddiqi, MD Dr. Siddiqi has received personal compensation in the range of $50,000-$99,999 for serving as a Consultant for Magnus Medical. Dr. Siddiqi has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Brainsway Ltd. Dr. Siddiqi has stock in Brainsway Ltd. Dr. Siddiqi has stock in Magnus Medical. Dr. Siddiqi has received intellectual property interests from a discovery or technology relating to health care.
Spancer Zhou, MD Miss Zhou has nothing to disclose.
Diana A. Rodriguez, Bachelor of Science Ms. Rodriguez has nothing to disclose.
Colin Bowyer, PhD Dr. Bowyer has nothing to disclose.
Jonathon Giftakis, PhD Dr. Giftakis has stock in Medtronic. Dr. Giftakis has received intellectual property interests from a discovery or technology relating to health care.
Marcus Ng, MD The institution of Dr. Ng has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Paladin Canada. The institution of Dr. Ng has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Paladin Canada. Dr. Ng has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Journal of Clinical Neurophysiology. The institution of Dr. Ng has received research support from Eisai. The institution of Dr. Ng has received research support from Paladin Canada. Dr. Ng has received publishing royalties from a publication relating to health care.
Joel Voss, PhD The institution of Prof. Voss has received research support from National Institutes of Health. Prof. Voss has received personal compensation in the range of $500-$4,999 for serving as a Study Section Member with National Institutes of Health.
Richard Rushmore, PhD Prof. Rushmore has nothing to disclose.
William W. Seeley, MD Dr. Seeley has received personal compensation in the range of $500-$4,999 for serving as a Consultant for GLG Council. Dr. Seeley has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Guidepoint Global Consulting. Dr. Seeley has received personal compensation in the range of $500-$4,999 for serving as a Consultant for BridgeBio. Dr. Seeley has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Biogen. Dr. Seeley has received personal compensation in the range of $10,000-$49,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Lyterian Therapeutics. The institution of Dr. Seeley has received research support from NIH. The institution of Dr. Seeley has received research support from Rainwater Charitable Foundation. The institution of Dr. Seeley has received research support from Bluefield Project to Cure FTD. The institution of Dr. Seeley has received research support from Chan-Zuckerberg Initiative.
Jagan Pillai, MD, PhD, FAAN Dr. Pillai has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Springer Nature. Dr. Pillai has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Current Treatment Options in Neurology. The institution of Dr. Pillai has received research support from Alzheimer's Association. The institution of Dr. Pillai has received research support from Keep Memory Alive Foundation . The institution of Dr. Pillai has received research support from NIA. Dr. Pillai has received personal compensation in the range of $500-$4,999 for serving as a Reviewer with DOD. Dr. Pillai has received personal compensation in the range of $500-$4,999 for serving as a Reviewer with RGC Hong kong.
Manuel X. Duval, PhD Mr. Duval has received personal compensation for serving as an employee of CND Life sciences.
Bonnie Glanz The institution of Ms. Glanz has received research support from CMSC. The institution of Ms. Glanz has received research support from NIH.
Johanna Seitz-Holland, MD, PhD Dr. Seitz-Holland has nothing to disclose.
Bailey Bellaire Bailey Bellaire has received personal compensation for serving as an employee of CND Life Sciences.
Cornelius Berberich, MD, PhD Dr. Berberich has nothing to disclose.
peter kochunov, PhD Prof. kochunov has nothing to disclose.
Calvin W. Howard, MD Dr. Howard has or had stock in CogNet.Dr. Howard has received intellectual property interests from a discovery or technology relating to health care.
Flavio DellAcqua, PhD Dr. DellAcqua has received personal compensation in the range of $0-$499 for serving as a Consultant for Nordic Imaging Lab. The institution of Dr. DellAcqua has received research support from ACimmune. Dr. DellAcqua has received intellectual property interests from a discovery or technology relating to health care. Dr. DellAcqua has received publishing royalties from a publication relating to health care.
Michael B. Seidman, MD Dr. Seidman has nothing to disclose.
Jordan Grafman, PhD Dr. Grafman has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Elsevier. Dr. Grafman has received research support from NIH. Dr. Grafman has received publishing royalties from a publication relating to health care.
Molly S. Hermiller, PhD Prof. Hermiller has nothing to disclose.
Daphne Holt, MD, PhD Dr. Holt has nothing to disclose.
Hyun Jo Kim No disclosure on file
Lisa McTeague No disclosure on file
Neill R. Graff-Radford, MD, FAAN The institution of Dr. Graff-Radford has received research support from Biogen. The institution of Dr. Graff-Radford has received research support from Lilly. The institution of Dr. Graff-Radford has received research support from Eisai. The institution of Dr. Graff-Radford has received research support from Biogen. Dr. Graff-Radford has received publishing royalties from a publication relating to health care.
Zachary Miller, MD Dr. Miller has nothing to disclose.
Carol Joseph, Student Ms. Joseph has nothing to disclose.
Yogesh Rathi, PhD The institution of Dr. Rathi has received research support from NIH.
Juan Carlos Baldermann The institution of Dr. Baldermann has received research support from Else Kröner-Fresenius-Stiftung.
James B. Leverenz, MD, FAAN Dr. Leverenz has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Acadia. Dr. Leverenz has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Biogen. Dr. Leverenz has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Eisai.
Jaime Vaquer-Alicea, PhD Dr. Vaquer-Alicea has nothing to disclose.
MARIA LUISA MANDELLI, PhD Prof. MANDELLI has nothing to disclose.
Lisa Wauters, PhD Dr. Wauters has a non-compensated relationship as a volunteer with National Aphasia Association that is relevant to AAN interests or activities.
Dost Ongur, MD, PhD Dr. Ongur has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for BD2. Dr. Ongur has received personal compensation in the range of $50,000-$99,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for JAMA Network. The institution of Dr. Ongur has received research support from NIH. Dr. Ongur has received personal compensation in the range of $5,000-$9,999 for serving as a Speaker at conference with Boehringer Ingelheim.
Marek Kubicki, MD, PhD The institution of Prof. Kubicki has received research support from NIH.
Ahmad Beyh, PhD Dr. Beyh has nothing to disclose.
Jourdan Parent, PhD Dr. Parent has received personal compensation for serving as an employee of CND Life Sciences.
Isaiah Kletenik, MD The institution of Dr. Kletenik has received research support from NIH.
Dirk Keene, MD, PhD Dirk Keene, MD, PhD has received publishing royalties from a publication relating to health care.
Nil Saez Calveras, MD Dr. Saez Calveras has nothing to disclose.
Kenichi Oishi, MD, PhD The institution of Dr. Oishi has received research support from National Institutes of Health. The institution of Dr. Oishi has received research support from Gates Venture. The institution of Dr. Oishi has received research support from NeuroXT. Dr. Oishi has received personal compensation in the range of $0-$499 for serving as a Grant reviewer with National Institutes of Health.
Tanuja Chitnis, MD, FAAN Dr. Chitnis has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Novartis. Dr. Chitnis has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Roche-Genentech. Dr. Chitnis has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Octave Biosciences. Dr. Chitnis has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Sanofi. The institution of Dr. Chitnis has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Novartis. The institution of Dr. Chitnis has received research support from Novartis. The institution of Dr. Chitnis has received research support from Sanofi. The institution of Dr. Chitnis has received research support from Octave. The institution of Dr. Chitnis has received research support from Genentech-Roche. The institution of Dr. Chitnis has received research support from Tiziana Life Sciences. The institution of Dr. Chitnis has received research support from Bristol-Myers Squibb. The institution of Dr. Chitnis has received research support from Wesley Clover.
T B Mr. B has nothing to disclose.
Matthew S. Dawson, PhD Dr. Dawson has nothing to disclose.
Sydney Morgan Miss Morgan has nothing to disclose.
Nikhil B. Ghayal, BS Mr. Ghayal has nothing to disclose.
Ofer Pasternak, PhD The institution of Dr. Pasternak has received research support from NIH. The institution of Dr. Pasternak has received research support from Michael J Fox Foundation.
David K. Johnson, PhD Prof. Johnson has nothing to disclose.
Kevin A. Caulfield, PhD Dr. Caulfield has nothing to disclose.
Rabea Schmahl, MSc Mrs. Schmahl has nothing to disclose.
Ivy Dickens, BS, BA Miss Dickens has nothing to disclose.
Sarrah Marcotte Miss Marcotte has received personal compensation for serving as an employee of CND Life Sciences.
M. M. Mesulam, MD, FAAN Dr. Mesulam has received publishing royalties from a publication relating to health care.
Young Min Cho, MD, PhD Prof. Cho has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Hanmi. The institution of Prof. Cho has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for LG Chemical. Prof. Cho has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Daewoong. Prof. Cho has received personal compensation in the range of $10,000-$49,999 for serving as an officer or member of the Board of Directors for Daewoong.
Robert S. Fisher, MD, PhD, FAAN Dr. Fisher has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Epi-Minder Study, Australia (Mark Cook, PI). Dr. Fisher has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for START study (Hal Blumenfeld, PI). Dr. Fisher has stock in Avails Medical stock options (drug level testing). Dr. Fisher has stock in Eysz stock options (eye-movement seizure detection). Dr. Fisher has stock in Irody stock options (health records databases). Dr. Fisher has stock in Smart-Monitor stock options (shake-detector watch). Dr. Fisher has stock in Zeto stock options, dry, wireless EEG. The institution of Dr. Fisher has received research support from NaviFUS (focused ultrasound).
Sylvain Bouix, PhD Mr. Bouix has nothing to disclose.
alan breier, MD Dr. breier has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Clexio Therapeutics . Dr. breier has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Neumarker . Dr. breier has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Bristol Meyer Sqibb. Dr. breier has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Terran Bioscience .
Parneet K. Grewal, MD The institution of Dr. Grewal has received research support from Bristol Myer Squibb Foundation. The institution of Dr. Grewal has received research support from IPSEN Global.
Todd D. Levine, MD Dr. Levine has received personal compensation for serving as an employee of CND life sciences . Dr. Levine has received personal compensation in the range of $100,000-$499,999 for serving as a Consultant for Nufactor. Dr. Levine has received personal compensation in the range of $50,000-$99,999 for serving as an Expert Witness for PNA. Dr. Levine has or had stock in CND Life Sciences.Dr. Levine has or had stock in Corinthian reference lab.
Gregory S. Day, MD, MSc, FAAN Dr. Day has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Arialys Therapeutics. Dr. Day has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for DynaMed (EBSCO Health). Dr. Day has or had stock in ANI Pharmaceuticals. The institution of Dr. Day has received research support from National Institutes of Health / NIA. The institution of Dr. Day has received research support from National Institutes of Health / NINDS. The institution of Dr. Day has received research support from Amgen Pharmaceuticals. The institution of Dr. Day has received research support from AVID Radiopharmaceuticals. Dr. Day has received personal compensation in the range of $500-$4,999 for serving as a Presenter at Annual Meeting (CME) with 好色先生. Dr. Day has received personal compensation in the range of $500-$4,999 for serving as a Content Development (CME) with PeerView, Inc. Dr. Day has received personal compensation in the range of $5,000-$9,999 for serving as a Content Development (CME) with Continuing 好色先生, Inc. Dr. Day has received personal compensation in the range of $5,000-$9,999 for serving as a Content Development (CME) with Ionis Pharmaceuticals. Dr. Day has received personal compensation in the range of $500-$4,999 for serving as a 好色先生al Case Development + Presentation (video) with PeerDirect (P\S\L Group). Dr. Day has received personal compensation in the range of $500-$4,999 for serving as a Content Development / Presentation (non-CME) with MJH Life Sciences (NeurologyLive). Dr. Day has a non-compensated relationship as a Clinical Director with Anti-NMDA Receptor Encephalitis Foundation that is relevant to AAN interests or activities.
Salvatore Citro, MD Dr. Citro has nothing to disclose.
Martha Shenton Martha Shenton has nothing to disclose.
Marco Catani, MD, PhD Prof. Catani has received personal compensation in the range of $0-$499 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Elsevier.
Gurkan Bebek, PhD Dr. Bebek has nothing to disclose.
Constantine Lyketsos Constantine Lyketsos has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Roche, Avanir, Karuna, Maplight, Axsome, GW Research Limited, Merck, EXCIVA GmbH, Otsuka, IntraCellular Therapies, Medesis, BMS, IQVIA. Constantine Lyketsos has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for IQVIA. The institution of Constantine Lyketsos has received research support from NIA. Constantine Lyketsos has received publishing royalties from a publication relating to health care. Constantine Lyketsos has received publishing royalties from a publication relating to health care.
Thomas Picht No disclosure on file
Shanu Roemer Shanu Roemer has nothing to disclose.
Yuto Uchida, MD, PhD Dr. Uchida has nothing to disclose.
Frederic Schaper, MD, PhD Dr. Schaper has nothing to disclose.
Michael Kahana, PhD Prof. Kahana has stock in Nia Therapeutics. Prof. Kahana has received intellectual property interests from a discovery or technology relating to health care.
Owen A. Ross, PhD Dr. Ross has nothing to disclose.
Dennis W. Dickson, MD Dr. Dickson has nothing to disclose.
Katharina Faust, MD Prof. Faust has nothing to disclose.
Maria Luisa Gorno Tempini, MD, PhD The institution of Dr. Gorno Tempini has received research support from the NIH.
Yuan Gao Miss Gao has nothing to disclose.
Boon Lead Tee, MD The institution of Boon Lead Tee, MD has received research support from Global Brain Health Institute. The institution of Boon Lead Tee, MD has received research support from Alzheimer's Association.
Arun Garimella Mr. Garimella has nothing to disclose.
Evelyn Lazar, MD Dr. Lazar has nothing to disclose.
Simon Kwon, PhD Dr. Kwon has nothing to disclose.
Roy L. Freeman, MD Dr. Freeman has received personal compensation in the range of $50,000-$99,999 for serving as a Consultant for Cutaneous Diagnostic Life Sciences. Dr. Freeman has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Vertex. Dr. Freeman has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Theravance. Dr. Freeman has received personal compensation in the range of $10,000-$49,999 for serving as an officer or member of the Board of Directors for Inhibikase. Dr. Freeman has received personal compensation in the range of $10,000-$49,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Elsevier. The institution of Dr. Freeman has received research support from NIH. The institution of Dr. Freeman has received research support from Theravance. The institution of Dr. Freeman has received research support from Biohaven. The institution of Dr. Freeman has received research support from Lundbeck. Dr. Freeman has received research support from Regeneron.
Veerle Visser-Vandewalle Veerle Visser-Vandewalle has nothing to disclose.
Rob Rouhl, MD, PhD Dr. Rouhl has nothing to disclose.
Sarah K. Kaufman, MD, PhD Dr. Kaufman has nothing to disclose.
Philip Mosley, MD, PhD Dr. Mosley has nothing to disclose.
JIACHEN LIAN, PhD Mr. LIAN has received personal compensation for serving as an employee of Meta. Mr. LIAN has received intellectual property interests from a discovery or technology relating to health care.
Ji Hyun H. Ko, PhD Dr. Ko has nothing to disclose.
Neslihan Yildiz Ozhan, MD Dr. Yildiz Ozhan has nothing to disclose.
Lisa Fosdick No disclosure on file
Rian L. Bogley Mr. Bogley has nothing to disclose.
Sandra Weintraub, PhD, FAAN Dr. Weintraub has nothing to disclose.