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2012 Annual Meeting | Peripheral Nerve Regeneration

Sunday 04/22/12
08:00 AM - 12:00 PM Add To Calendar
This program will be presented both in-person and online
This program is not expected to be available in the meeting's On Demand product.
Integrated Neuroscience
Douglas W. Zochodne, MD, Ahmet Hoke, MD, PhD, FAAN
Peripheral Nerve
No CME available

Program Evaluations

Event Timeline
08:00 AM - 08:15 AM Revitalizing Nerves: The Long Term Denervated Stump
Ahmet Hoke, MD, PhD, FAAN
08:00 AM - 12:00 PM Break
08:00 AM - 12:00 PM Abstract 001 - A Screening Assay for Myelin Protein Zero Mutants: Unfolded Protein Response Activation and Its Significant Reduction by Curcumin Treatment
08:00 AM - 12:00 PM Abstract 001 - Degeneration and Regeneration of Peripheral Motor Axons Is Impaired in Mice Heterozygously Deficient for the Myelin Protein P0 Gene
08:00 AM - 12:00 PM Abstract 002 - Evaluation of Dermal Myelinated Fibers in Diabetic Polyneuropathy
08:00 AM - 12:00 PM Abstract 002 - Immune Complex-Induced Inflammation as a Mechanism of Inhibition of Peripheral Nerve Regeneration
08:00 AM - 12:00 PM Abstract 003 - Virtual Demyelination and Tight Junction Defect in PMP22 Deficiency
08:00 AM - 12:00 PM Abstract 003 - Comparison of Recovery of Tactile Function and Sensation after Median or Ulnar Nerve Lesions Repaired by Suture or Nerve Guide
08:00 AM - 12:00 PM Abstract 004 - Useful Biomarkers for the Diagnosis of Painful Diabetic Neuropathy
08:00 AM - 12:00 PM Abstract 004 - RAGE-Dependent Signaling in Peripheral Neurons and Macrophages Regulates Peripheral Nerve Repair
08:00 AM - 12:00 PM Abstract 005 - Neuropathy Due to Amiodarone: Schwann Cells Are the Target
08:00 AM - 12:00 PM Abstract 005 - Reduced Kv1-Channel Localization in Juxtaparanodal Regions Mediate Peripheral Nerve Hyperexcitability in Diabetic Neuropathy
08:00 AM - 12:00 PM Abstract 006 - Regulatory T Cells Determine Disease Severity in Experimental Autoimmune Neuropathies
08:00 AM - 12:00 PM Abstract 007 - Bioenergetic Metabolites in the Diabetic Peripheral Nervous System
08:00 AM - 12:00 PM Abstract 008 - Anti-Ganglioside Antibodies Induce Neuropathy Via Fc[gamma] Receptors in Mice
08:00 AM - 12:00 PM Abstract 009 - Mass Spectrophotometric Analysis of Focal Neural Amyloid Deposition Reveals Isolated Non-Mutated ApoA1 Amylodosis
08:00 AM - 12:00 PM Abstract 010 - Methylmalonic Acid Accumulation and the Development of Peripheral Neuropathy
08:15 AM - 08:30 AM Axonal Damage: Mechanisms of Damage in Chemotherapeutic and Other Toxic Neuropathies
Anthony J. Windebank, MD, FAAN
08:30 AM - 08:45 AM When to Operate: Traumatic Nerve Lesions
Rajiv Midha
08:45 AM - 09:00 AM Steps in the Regenerative Process
Douglas W. Zochodne, MD
09:00 AM - 09:15 AM Neurotophins and Other Growth Factors in Nerve Regeneration
Ahmet Hoke, MD, PhD, FAAN
09:15 AM - 09:30 AM Novel Forms of Nerve Repair
Anthony J. Windebank, MD, FAAN
09:30 AM - 09:45 AM Advances in Nerve Repair
Rajiv Midha
09:45 AM - 10:00 AM Roadblocks to Nerve Repair
Douglas W. Zochodne, MD
10:00 AM - 11:00 AM Poster Rounds
11:00 AM - 11:30 AM Data Blitz
11:30 AM - 12:00 PM Panel Discussion
Faculty Disclosures
Douglas W. Zochodne, MD No disclosure on file
Ahmet Hoke, MD, PhD, FAAN Dr. Hoke has received personal compensation in the range of $50,000-$99,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Disarm. Dr. Hoke has received personal compensation in the range of $10,000-$49,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Elsevier. Dr. Hoke has received personal compensation in the range of $5,000-$9,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Annals of Clinical and Translational Neurology. Dr. Hoke has received personal compensation in the range of $5,000-$9,999 for serving as an Expert Witness for Burke and Thomas. Dr. Hoke has received stock or an ownership interest from Axoprotego Therapeutics. The institution of Dr. Hoke has received research support from NIH. The institution of Dr. Hoke has received research support from DOD. The institution of Dr. Hoke has received research support from Dr. Miriam and Sheldon G. Adelson Medical Research Foundation. The institution of Dr. Hoke has received research support from Foundation for Peripheral Neuropathy. Dr. Hoke has received intellectual property interests from a discovery or technology relating to health care.
Anthony J. Windebank, MD, FAAN Dr. Windebank has nothing to disclose.
Rajiv Midha No disclosure on file
Arthur Hays, MD No disclosure on file
No disclosure on file
Cory C. Toth, MD No disclosure on file
David S. Knopman, MD, FAAN Dr. Knopman has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for DIAN TU study. The institution of Dr. Knopman has received research support from NIH.
Ronald C. Petersen, MD, PhD, FAAN Dr. Petersen has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Roche. Dr. Petersen has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Genentech. Dr. Petersen has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Eli Lilly and Co.. Dr. Petersen has received personal compensation in the range of $0-$499 for serving as a Consultant for Eisai, Inc.. Dr. Petersen has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Novo Nordisk. Dr. Petersen has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Novartis. Dr. Petersen has received publishing royalties from a publication relating to health care. Dr. Petersen has received publishing royalties from a publication relating to health care. Dr. Petersen has received publishing royalties from a publication relating to health care. Dr. Petersen has a non-compensated relationship as a Board of Directors with American Brain Foundation that is relevant to AAN interests or activities.
Val J. Lowe, MD Dr. Lowe has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for AVID Radiopharmaceutical. Dr. Lowe has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Eisai Inc. The institution of Dr. Lowe has received research support from AVID Radiopharmaceuticals.
David H. Miller, MD, MBChB, FRCP No disclosure on file
Olga Ciccarelli, MD, PhD, FRCP Prof. Ciccarelli has received personal compensation in the range of $0-$499 for serving as a Consultant for Lundebeck. Prof. Ciccarelli has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Novartis. Prof. Ciccarelli has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Biogen. Prof. Ciccarelli has received personal compensation in the range of $0-$499 for serving on a Speakers Bureau for Merck. Prof. Ciccarelli has received personal compensation in the range of $10,000-$49,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for NEUROLOGY Journal.
Kazim A. Sheikh, MD The institution of Dr. Sheikh has received research support from NIH. The institution of Dr. Sheikh has received research support from DoD.
Christian Krarup, MD, DMSc, FRcP, FAAN Dr. Krarup has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Shire/Takeda. Dr. Krarup has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Shire/Takeda. Dr. Krarup has received publishing royalties from a publication relating to health care.
Hans-Peter Hartung, MD, FAAN Dr. Hartung has received personal compensation in the range of $500-$4,999 for serving as a Consultant for BMS Celgene. Dr. Hartung has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Geneuro. Dr. Hartung has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Novartis. Dr. Hartung has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Novartis. Dr. Hartung has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Merck. Dr. Hartung has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Bayer. Dr. Hartung has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for TG Therapeutics. Dr. Hartung has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Roche. Dr. Hartung has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Frontiers Neurology.
Gang Zhang, MD, PhD No disclosure on file
Michael Levy, MD, PhD, FAAN Dr. Levy has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Mitsubishi Pharma. Dr. Levy has received personal compensation in the range of $500-$4,999 for serving as a Consultant for UCB Pharma. Dr. Levy has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Sanofi. Dr. Levy has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Alexion. Dr. Levy has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Horizon. Dr. Levy has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Genentech. Dr. Levy has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Elsevier. Dr. Levy has received personal compensation in the range of $10,000-$49,999 for serving as an Expert Witness for Various law firms. The institution of Dr. Levy has received research support from National Institutes Health.
Gerd Meyer Zu Horste, MD Dr. Meyer Zu Horste has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Immunovant, Roche. Dr. Meyer Zu Horste has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Amgen, Alexion. The institution of Dr. Meyer Zu Horste has received research support from Merck KGaA. The institution of Dr. Meyer Zu Horste has received research support from Roche. Dr. Meyer Zu Horste has received intellectual property interests from a discovery or technology relating to health care.
Agnes Patzko, MD No disclosure on file
Amanda C. Peltier, MD, MS Dr. Peltier has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Alnylam. Dr. Peltier has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for astrazeneca. Dr. Peltier has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for CSL Behring. Dr. Peltier has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Csl Behring. Dr. Peltier has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for argenx. Dr. Peltier has received personal compensation in the range of $5,000-$9,999 for serving on a Speakers Bureau for alnylam. Dr. Peltier has received personal compensation in the range of $10,000-$49,999 for serving on a Speakers Bureau for astrazeneca. Dr. Peltier has received personal compensation in the range of $10,000-$49,999 for serving as an Expert Witness for Goldman Ismail. The institution of Dr. Peltier has received research support from NIH. The institution of Dr. Peltier has received research support from CSL Behring.
Michael E. Shy, MD, FAAN Dr. Shy has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Applied Therapeutics. The institution of Dr. Shy has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for DTx Pharma. The institution of Dr. Shy has received research support from NIH. The institution of Dr. Shy has received research support from Muscular Dystrophy Association. The institution of Dr. Shy has received research support from Charcot Marie Tooth Association. The institution of Dr. Shy has received research support from Applied Therapeutics.
John A. Kamholz, MD Dr. Kamholz has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Guidepoint. The institution of Dr. Kamholz has received research support from HDSA.
Jun Li, MD, PhD, FAAN The institution of Dr. Li has received personal compensation in the range of $500-$4,999 for serving as a Consultant for FDA. The institution of Dr. Li has received research support from NIH. Dr. Li has a non-compensated relationship as a Associate Editor of ACTN journal with ANA that is relevant to AAN interests or activities.
Lawrence G. Wrabetz, MD No disclosure on file
Eva Feldman, MD, PhD, FAAN The institution of Dr. Feldman has received research support from National Institutes of Health. The institution of Dr. Feldman has received research support from Centers for Disease Control and Prevention / Agency for Toxic Substances and Disease Registry. The institution of Dr. Feldman has received research support from Juvenile Diabetes Research Foundation. Dr. Feldman has received intellectual property interests from a discovery or technology relating to health care. Dr. Feldman has a non-compensated relationship as a Editorial Board Member with Journal of the Peripheral Nervous System, Experimental Neurology, Nature Neurology Reviews, Neurobiology of Disease, NeuroRx, Journal of Neurology Neurosurgery and Psychiatry, Scientific Reports, Lancet Neurology, Med (Cell Press Journal) that is relevant to AAN interests or activities. Dr. Feldman has a non-compensated relationship as a Editor-in-Chief with Oxford University Press Contemporary Neurology Series that is relevant to AAN interests or activities. Dr. Feldman has a non-compensated relationship as a Membership Committee Member, Strategic Planning Committee Member, and Chair of Section 07 with National Academy of Medicine that is relevant to AAN interests or activities. Dr. Feldman has a non-compensated relationship as a Associate Editor with Annals of Neurology that is relevant to AAN interests or activities. Dr. Feldman has a non-compensated relationship as a Governance Committee Chair with American Neurological Association that is relevant to AAN interests or activities. Dr. Feldman has a non-compensated relationship as a Membership Committee Member, Strategic Planning Committee Member, Chair of Section 07, Neuroscience Forum, Council Member with National Academy of Medicine that is relevant to AAN interests or activities. Dr. Feldman has a non-compensated relationship as a Committee on Making ALS a Livable Disease Member with National Academy of Sciences, Engineering, and Medicine that is relevant to AAN interests or activities. Dr. Feldman has a non-compensated relationship as a Member, Blueprint Neurotherapeutics Network for Biologics (BPN-Biologics) External Oversight Committee with National Institutes of Health that is relevant to AAN interests or activities.
Vinay Chaudhry, MD, FAAN Dr. Chaudhry has received intellectual property interests from a discovery or technology relating to health care. Dr. Chaudhry has received intellectual property interests from a discovery or technology relating to health care. Dr. Chaudhry has received intellectual property interests from a discovery or technology relating to health care. Dr. Chaudhry has received intellectual property interests from a discovery or technology relating to health care. Dr. Chaudhry has received intellectual property interests from a discovery or technology relating to health care. Dr. Chaudhry has received intellectual property interests from a discovery or technology relating to health care. Dr. Chaudhry has received intellectual property interests from a discovery or technology relating to health care. Dr. Chaudhry has received intellectual property interests from a discovery or technology relating to health care. Dr. Chaudhry has received intellectual property interests from a discovery or technology relating to health care. Dr. Chaudhry has received intellectual property interests from a discovery or technology relating to health care. Dr. Chaudhry has received intellectual property interests from a discovery or technology relating to health care.
Adam Loavenbruck, MD Dr. Loavenbruck has nothing to disclose.
Christopher J. Klein, MD, FAAN Dr. Klein has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Takeda. Dr. Klein has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Sangamo Therapeutics . Dr. Klein has received personal compensation in the range of $500-$4,999 for serving as a Consultant for NMD Pharma.
Thierry Kuntzer, MD No disclosure on file
Hsinlin T. Cheng, MD Dr. Cheng has nothing to disclose.
Cynthia A. Massaad, PhD No disclosure on file
Ling Ling Rong, MD Dr. Rong has nothing to disclose.
Lan He No disclosure on file
A. Gordon Smith, MD, FAAN Dr. Smith has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Alexion. Dr. Smith has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Argenx. Dr. Smith has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Merz. Dr. Smith has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Sangamo. Dr. Smith has received personal compensation in the range of $500-$4,999 for serving as a Consultant for US Department of Justice. Dr. Smith has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Janssen. Dr. Smith has received personal compensation in the range of $0-$499 for serving on a Scientific Advisory or Data Safety Monitoring board for Eidos. Dr. Smith has received personal compensation in the range of $0-$499 for serving on a Scientific Advisory or Data Safety Monitoring board for Lexicon. Dr. Smith has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Alexion. The institution of Dr. Smith has received research support from NIH (NINDS, NIDDK). Dr. Smith has received publishing royalties from a publication relating to health care. Dr. Smith has received personal compensation in the range of $0-$499 for serving as a Study Section with NIH.
J. R. Singleton, MD Dr. Singleton has received research support from NIH.
Clifford R. Jack, Jr., MD The institution of Dr. Jack has received research support from NIH. The institution of Dr. Jack has received research support from Alexander Family Alzheimer's Disease Research Professorship of the Mayo Clinic.
Qing Yan No disclosure on file
Clifton L. Gooch, MD, FAAN Dr. Gooch has received publishing royalties from a publication relating to health care. Dr. Gooch has received publishing royalties from a publication relating to health care.
Judith Bellmann-Strobl, MD Judith Bellmann-Strobl, MD has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Roche. Judith Bellmann-Strobl, MD has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Merck. Judith Bellmann-Strobl, MD has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Sanofi Genzyme. Judith Bellmann-Strobl, MD has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Roche. The institution of Judith Bellmann-Strobl, MD has received research support from Bayer. The institution of Judith Bellmann-Strobl, MD has received research support from NEMOS.
Jennifer Zenker No disclosure on file
Jerzy P. Szaflarski, MD, PhD, FAAN Dr. Szaflarski has received personal compensation in the range of $500-$4,999 for serving as a Consultant for UCB Pharma. Dr. Szaflarski has received personal compensation in the range of $500-$4,999 for serving as a Consultant for LivaNova Inc. Dr. Szaflarski has received personal compensation in the range of $500-$4,999 for serving as a Consultant for PureTech Health. Dr. Szaflarski has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Gidley, Sarli & Marusak, LLP. Dr. Szaflarski has received personal compensation in the range of $5,000-$9,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Elsevier. Dr. Szaflarski has received personal compensation in the range of $5,000-$9,999 for serving as an Expert Witness for Law Firm. Dr. Szaflarski has stock in AdCel Biopharma, LLC. Dr. Szaflarski has stock in iFovea.
E M. Bebin, MD, FAAN Dr. Bebin has received personal compensation for serving as an employee of Springworks Therapeutics. Dr. Bebin has received personal compensation for serving as an employee of Apertura Gene Therapy. Dr. Bebin has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Springworks Therapeutics. Dr. Bebin has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Apertura. The institution of Dr. Bebin has received research support from NINDS. The institution of Dr. Bebin has received research support from FDA Orphan Drug Program.
Michelle M. Mielke, PhD Dr. Mielke has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Merck. Dr. Mielke has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Eisai. Dr. Mielke has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Eli Lilly. Dr. Mielke has received personal compensation in the range of $500-$4,999 for serving as a Consultant for LabCorp. Dr. Mielke has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Roche. Dr. Mielke has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Siemens Healthineers. Dr. Mielke has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Sunbird Bio. Dr. Mielke has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Eisai. Dr. Mielke has received personal compensation in the range of $5,000-$9,999 for serving on a Speakers Bureau for Roche. Dr. Mielke has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Novo Nordisk.
Christian Kamm, MD No disclosure on file
Ian T. Rossman, MD, PhD No disclosure on file