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2017 Annual Meeting | S17 - Movement Disorders: Ataxia and the Cerebellum

Monday 04/24/17
03:30 PM - 05:30 PM Add To Calendar
This program will be presented both in-person and online
This program is not expected to be available in the meeting's On Demand product.
Scientific Platform Session
Movement Disorders
2.00 CME credits
Event Timeline
03:30 PM - 05:30 PM Abstract 001 - ATXN2 antisense therapy improves SCA2 mouse motor and Purkinje cell electrophysiological phenotypes.
Daniel R. Scoles, PhD, FAAN
03:30 PM - 05:30 PM Abstract 002 - Fragile X Gray Zone Alleles are associated with Better Global Motor Function in an Elderly Community Population
Deborah Hall, MD, PhD, FAAN
03:30 PM - 05:30 PM Abstract 003 - RT001 First-in Human Clinical Trial Demonstrates Safety, Favorable Pharmacokinetics, and Early Signals of Efficacy in Friedreich’s Ataxia
Theresa A. Zesiewicz, MD
03:30 PM - 05:30 PM Abstract 004 - Exome Sequencing Offers a Comprehensive Genetic Evaluation and High Diagnostic Rate for Ataxia-related Disorders
03:30 PM - 05:30 PM Abstract 005 - EPI-743 (Alpha-tocotrienol Quinone) Demonstrates Long-Term Improvement in Neurological Function and Disease Progression in Friedreich's Ataxia
Theresa A. Zesiewicz, MD
03:30 PM - 05:30 PM Abstract 006 - Cerebellar Pathology in Early Onset and Late Onset Essential Tremor
Sheng-Han Kuo, MD, FAAN
03:30 PM - 05:30 PM Abstract 007 - Structure-Phenotype relationships in ATP1A3 (Na,K-ATPase) diseases
03:30 PM - 05:30 PM Abstract 008 - In vivo drug discovery for progressive supranuclear palsy using a novel zebrafish model
Edward Burton
05:05 PM - 05:30 PM Speaker Discussion
Brent L. Fogel, MD, PhD, FAAN
Faculty Disclosures
David A. Bennett, MD Dr. Bennett has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Origent. Dr. Bennett has received personal compensation in the range of $10,000-$49,999 for serving on a Scientific Advisory or Data Safety Monitoring board for AbbVie. Dr. Bennett has received personal compensation in the range of $5,000-$9,999 for serving as a Study section, DMC, NACA Council with NIH. Dr. Bennett has received personal compensation in the range of $10,000-$49,999 for serving as a invited lectures with AMCs. Dr. Bennett has received personal compensation in the range of $5,000-$9,999 for serving as a invited paper with National Academy of Sciences. Dr. Bennett has received personal compensation in the range of $5,000-$9,999 for serving as a lecture with National Academy of Neuropsychology.
Gregory R. Bonomo, MD No disclosure on file
Aron S. Buchman, MD No disclosure on file
Christopher Gomez, MD, PhD Dr. Gomez has nothing to disclose.
Susan L. Perlman, MD Dr. Perlman has nothing to disclose.
Stefan M. Pulst, MD, FAAN Dr. Pulst has received personal compensation in the range of $500-$4,999 for serving as a Consultant for venrock. Dr. Pulst has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Arrowhead. Dr. Pulst has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Leverna. Dr. Pulst has received personal compensation in the range of $10,000-$49,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for AAN. Dr. Pulst has received personal compensation in the range of $500-$4,999 for serving as an Expert Witness for Leninthal LLC. The institution of Dr. Pulst has received research support from NINDS. Dr. Pulst has received intellectual property interests from a discovery or technology relating to health care.
Allison Brashear, MD, MBA, FAAN Dr. Brashear has received personal compensation for serving as an employee of McKnight Brain Res Found. Dr. Brashear has received personal compensation for serving as an employee of American Board of Psychiatry and Neurology. Dr. Brashear has received personal compensation in the range of $10,000-$49,999 for serving as an officer or member of the Board of Directors for ABPN. Dr. Brashear has received personal compensation in the range of $10,000-$49,999 for serving as an officer or member of the Board of Directors for McKnight Brain Research Foundation i. Dr. Brashear has received personal compensation in the range of $0-$499 for serving as an officer or member of the Board of Directors for Care Directions- start up . Dr. Brashear has stock in Caredirections . The institution of Dr. Brashear has received research support from NINDS. Dr. Brashear has received publishing royalties from a publication relating to health care. Dr. Brashear has received personal compensation in the range of $500-$4,999 for serving as a Special government employee and study section reviewer with NIH. Dr. Brashear has received personal compensation in the range of $0-$499 for serving as a Adminstrative board -travel reimbursement with AAMC.
David R. Lynch, MD, PhD The institution of Dr. Lynch has received research support from reata. The institution of Dr. Lynch has received research support from PTC. Dr. Lynch has received intellectual property interests from a discovery or technology relating to health care.
Clifton L. Gooch, MD, FAAN Dr. Gooch has received publishing royalties from a publication relating to health care. Dr. Gooch has received publishing royalties from a publication relating to health care.
Theresa A. Zesiewicz, MD Dr. Zesiewicz has received personal compensation for serving as an employee of Medscape. Dr. Zesiewicz has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Lexeo. Dr. Zesiewicz has received personal compensation in the range of $10,000-$49,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Steminent. Dr. Zesiewicz has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Larimar. Dr. Zesiewicz has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Biohaven. Dr. Zesiewicz has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Biogen. Dr. Zesiewicz has received intellectual property interests from a discovery or technology relating to health care. Dr. Zesiewicz has received intellectual property interests from a discovery or technology relating to health care. Dr. Zesiewicz has received intellectual property interests from a discovery or technology relating to health care.
Elan D. Louis, MD, MS, FAAN Dr. Louis has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Wolters Kluwer - Merritt's Textbook of Neurology. Dr. Louis has received personal compensation in the range of $5,000-$9,999 for serving as an Expert Witness for Legal Firm. The institution of Dr. Louis has received research support from National Institutes of Health. Dr. Louis has received publishing royalties from a publication relating to health care. Dr. Louis has a non-compensated relationship as a Board of Directors with International Essential Tremor Foundation that is relevant to AAN interests or activities. Dr. Louis has a non-compensated relationship as a Medical Advisory Board with HopeNET that is relevant to AAN interests or activities.
Elizabeth M. Berry-Kravis, MD, PhD The institution of Dr. Berry-Kravis has received research support from NIH. The institution of Dr. Berry-Kravis has received research support from Ionis. The institution of Dr. Berry-Kravis has received research support from Zynerba. The institution of Dr. Berry-Kravis has received research support from Roche. The institution of Dr. Berry-Kravis has received research support from CDC. The institution of Dr. Berry-Kravis has received research support from FRAXA Research Foundation. The institution of Dr. Berry-Kravis has received research support from GeneTx. The institution of Dr. Berry-Kravis has received research support from Angelman Syndrome Foundation. The institution of Dr. Berry-Kravis has received research support from Acadia. The institution of Dr. Berry-Kravis has received research support from Ultragenyx. The institution of Dr. Berry-Kravis has received research support from Mallinckrodt. The institution of Dr. Berry-Kravis has received research support from Together Strong Foundation. The institution of Dr. Berry-Kravis has received research support from Zevra. The institution of Dr. Berry-Kravis has received research support from Taysha. The institution of Dr. Berry-Kravis has received research support from Tetra. The institution of Dr. Berry-Kravis has received research support from Neuren.
Kathryn J. Swoboda, MD Dr. Swoboda has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Biogen. Dr. Swoboda has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Biogen. The institution of Dr. Swoboda has received research support from Biogen.
Omid Omidvar, MD No disclosure on file
Puneet Opal, MD, PhD Dr. Opal has received personal compensation in the range of $500-$4,999 for serving as a Consultant for reata. Dr. Opal has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for ACTN. Dr. Opal has received personal compensation in the range of $5,000-$9,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for JCI. The institution of Dr. Opal has received research support from NIH. Dr. Opal has received intellectual property interests from a discovery or technology relating to health care.
Laurie J. Ozelius, PhD The institution of Dr. Ozelius has received research support from NIH. Dr. Ozelius has received intellectual property interests from a discovery or technology relating to health care.
Karla P. Figueroa Ms. Figueroa has nothing to disclose.
Daniel R. Scoles, PhD, FAAN The institution of Dr. Scoles has received research support from NIH.
Ludy C. Shih, MD, FAAN Dr. Shih has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Encora Therapeutics. Dr. Shih has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for WCG Medavante. Dr. Shih has received personal compensation in the range of $50,000-$99,999 for serving as a Consultant for Ventyx Biosciences. Dr. Shih has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Aspen Neuroscience. Dr. Shih has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Medtronic. Dr. Shih has received personal compensation in the range of $5,000-$9,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Wiley. The institution of Dr. Shih has received research support from Praxis Precision Medicines. The institution of Dr. Shih has received research support from Tremor Research Group. The institution of Dr. Shih has received research support from Denali Therapeutics. The institution of Dr. Shih has received research support from University of Rochester. Dr. Shih has received personal compensation in the range of $500-$4,999 for serving as a Consultant with German Accelerator. Dr. Shih has received personal compensation in the range of $500-$4,999 for serving as a Grant Reviewer with National Institutes of Health. Dr. Shih has received personal compensation in the range of $500-$4,999 for serving as a Grant Reviewer with Michael J. Fox Foundation. Dr. Shih has received personal compensation in the range of $500-$4,999 for serving as a Grant Reviewer with Johns Hopkins. Dr. Shih has a non-compensated relationship as a Co-chair, Scientific Program Committee and President-Elect with American Society of Experimental Neurotherapeutics that is relevant to AAN interests or activities.
Deborah Hall, MD, PhD, FAAN Dr. Hall has received personal compensation in the range of $10,000-$49,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for 好色先生. Dr. Hall has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Elsevier - Parkinsonism and Related Disorders. Dr. Hall has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Annals of Neurology. The institution of Dr. Hall has received research support from Parkinson's Foundation. The institution of Dr. Hall has received research support from CHDI. The institution of Dr. Hall has received research support from Uniqure. The institution of Dr. Hall has received research support from NIH.
Kelly Sullivan, PhD Dr. Sullivan has received intellectual property interests from a discovery or technology relating to health care.
Brent L. Fogel, MD, PhD, FAAN Dr. Fogel has received personal compensation in the range of $0-$499 for serving as an officer or member of the Board of Directors for National Ataxia Foundation. Dr. Fogel has received personal compensation in the range of $0-$499 for serving as an officer or member of the Board of Directors for Ataxia Global Initiative. Dr. Fogel has received personal compensation in the range of $0-$499 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Neurology Today. Dr. Fogel has received personal compensation in the range of $0-$499 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Neurology Genetics. Dr. Fogel has received personal compensation in the range of $0-$499 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Frontiers in Genetics. Dr. Fogel has received personal compensation in the range of $0-$499 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Genes. Dr. Fogel has received personal compensation in the range of $0-$499 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Neuromarkers. The institution of Dr. Fogel has received research support from the National Institutes of Health. The institution of Dr. Fogel has received research support from the National Ataxia Foundation. The institution of an immediate family member of Dr. Fogel has received research support from the National Institutes of Health, the National Science Foundation, and the Department of Defense. The institution of Dr. Fogel has received research support from US Department of Defense .
No disclosure on file
Frank Bennett, PhD No disclosure on file
Sheng-Han Kuo, MD, FAAN Dr. Kuo has nothing to disclose.
Edward Burton No disclosure on file
Thomas Otis, MD No disclosure on file
Jared Cook No disclosure on file
Aisha M. Ali, MD Dr. Ali has nothing to disclose.
Amanda S. Lindy, PhD Dr. Lindy has received personal compensation for serving as an employee of GeneDx.
Dianalee McKnight, PhD Dr. McKnight has nothing to disclose.
Frederic Heerinckx, PharmD No disclosure on file
William J. Tate No disclosure on file
Phyllis Faust Phyllis Faust has nothing to disclose.
Bichum Ouyang Bichum Ouyang has nothing to disclose.